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Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
- Title
- Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
- Authors
- Park, Ik Hyun; Yang, Jeong Hoon; Jang, Woo Jin; Chun, Woo Jung; Oh, Ju Hyeon; Park, Yong Hwan; Yu, Cheol Woong; Kim, Hyun-Joong; Kim, Bum Sung; Jeong, Jin-Ok; Lee, Hyun Jong; Gwon, Hyeon-Cheol
- Ewha Authors
- 장우진
- SCOPUS Author ID
- 장우진
- Issue Date
- 2020
- Journal Title
- JOURNAL OF CLINICAL MEDICINE
- ISSN
- 2077-0383
- Citation
- JOURNAL OF CLINICAL MEDICINE vol. 9, no. 11
- Keywords
- extracorporeal cardiopulmonary resuscitation; in-hospital cardiac arrest; low-flow time; vasoactive inotropic score
- Publisher
- MDPI
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divided into two groups: patients undergoing extracorporeal membrane oxygenation as an adjunct to standard cardiopulmonary resuscitation for less than 38 min (n = 110) or for longer than 38 min (n = 73). The ECPR <= 38 min group had a significantly greater incidence of survival to discharge compared to the ECPR > 38 min group (40.0% versus 24.7%, p = 0.032). The incidence of good neurologic outcomes at discharge tended to be greater in the ECPR <= 38 min group than in the ECPR > 38 min group (35.5% versus 24.7%, p = 0.102). The incidences of limb ischemia (p = 0.354) and stroke (p = 0.805) were similar between the two groups, but major bleeding occurred less frequently in the ECPR <= 38 min group compared to the ECPR > 38 min group (p = 0.002). Low-flow time <= 38 min may reduce the risk of mortality and fatal neurologic damage and could be a measure of optimal management in patients with IHCA.
- DOI
- 10.3390/jcm9113588
- Appears in Collections:
- 의료원 > 의료원 > Journal papers
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