View : 537 Download: 0
Evaluation and management of difficult-to-Treat and severe asthma: An expert opinion from the Korean Academy of asthma, allergy and clinical immunology, the working group on severe asthma
- Title
- Evaluation and management of difficult-to-Treat and severe asthma: An expert opinion from the Korean Academy of asthma, allergy and clinical immunology, the working group on severe asthma
- Authors
- Kim B.-K.; Park S.-Y.; Ban G.-Y.; Kim M.-A.; Lee J.-H.; An J.; Shim J.-S.; Lee Y.; Won H.-K.; Lee H.Y.; Sohn K.-H.; Kang S.-Y.; Park S.Y.; Lee H.; Kim M.-H.; Kwon J.-W.; Yoon S.-Y.; Rhee C.K.; Moon J.-Y.; Lee T.; Kim S.R.; Park J.S.; Kim S.-H.; Park H.-W.; Jeong J.W.; Koh Y.-I.; Oh Y.-M.; Jang A.-S.; Yoo K.H.; Cho Y.S.; Korean Academy of Asthma; Allergy; and Clinical Immunology (KAACI); Working Group on Severe Asthma
- Ewha Authors
- 김민혜; 심지수
- SCOPUS Author ID
- 김민혜; 심지수
- Issue Date
- 2020
- Journal Title
- Allergy, Asthma and Immunology Research
- ISSN
- 2092-7355
- Citation
- Allergy, Asthma and Immunology Research vol. 12, no. 6, pp. 910 - 933
- Keywords
- Biologics; Diagnosis; Eosinophil; Expert opinion; IgE; IL4; IL5; Severe asthma; Treatment
- Publisher
- Korean Academy of Asthma, Allergy and Clinical Immunology
- Indexed
- SCIE; SCOPUS; KCI
- Document Type
- Review
- Abstract
- Severe asthma (SA) presents in about 3%–5% of adult asthmatics and is responsible for over 60% of asthma-related medical expenses, posing a heavy socioeconomic burden. However, to date, a precise definition of or clear diagnostic criteria for SA have not been established, and therefore, it has been challenging for clinicians to diagnose and treat this disease. Currently, novel biologics targeting several molecules, such as immunoglobulin E, interleukin (IL)5, and IL4/IL13, have emerged, and many new drugs are under development. These have brought a paradigm shift in understanding the mechanism of SA and have also provided new treatment options. However, we need to agree on a precise definition of and its diagnostic criteria for SA. Additionally, it is necessary to explain the diagnostic criteria and to summarize current standard and additional treatment options. This review is an experts' opinion on SA from the Korean Academy of Asthma, Allergy, and Clinical Immunology, the Working Group on Severe Asthma, and aims to provide a definition of and diagnostic criteria for SA, and propose future direction for SA diagnosis and management in Korea. Copyright © 2020 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease.
- DOI
- 10.4168/aair.2020.12.6.910
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML