Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 조인정 | * |
dc.date.accessioned | 2020-08-24T16:30:22Z | - |
dc.date.available | 2020-08-24T16:30:22Z | - |
dc.date.issued | 2019 | * |
dc.identifier.issn | 2586-7210 | * |
dc.identifier.other | OAK-27718 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/255244 | - |
dc.description.abstract | BACKGROUND: Limited data are available on the prognosis of progressive mitral stenosis (MS). We evaluated the factors associated with adverse events in patients with progressive MS. METHODS: We retrospectively analyzed 259 consecutive patients with pure progressive MS with a mitral valve area (MVA) between 1.5 and 2.0 cm2. The primary outcome measures were a composite endpoint of cardiac death, heart failure hospitalization, mitral valve surgery or percutaneous mitral valvuloplasty, and ischemic stroke. RESULTS: The mean patient age was 62 ± 12 years, and the mean MVA was 1.71 ± 0.15 cm2. Over a median follow-up duration of 52 months, a total of 41 patients (18.3%) experienced the composite endpoint. In multivariable Cox regression analysis, prior stroke (hazard ratio [HR], 4.54; 95% confidence interval [CI], 2.16–9.54; p < 0.001) and left atrial volume index (LAVI) of > 50 mL/m2 (HR, 4.45; 95% CI, 1.31–15.31; p = 0.017) were identified as independent predictors of the composite endpoint, even after adjusting for age and sex. Patients with a LAVI ≤ 50 mL/m2 demonstrated favorable event-free survival compared with those with a LAVI > 50 mL/m2 in either the overall population (p < 0.001) or asymptomatic patients (p = 0.002). Atrial fibrillation (AF), left ventricular mass index (LVMI), MVA, and mean diastolic pressure were factors independently associated with LAVI (all p < 0.05). CONCLUSIONS: A deleterious impact of a high LAVI on outcome was observed in patients with progressive MS. The LAVI was mainly influenced by the presence of AF, the severity of MS, and LVMI in this population. © 2019 Korean Society of Echocardiography. | * |
dc.language | English | * |
dc.publisher | Korean Society of Echocardiography | * |
dc.subject | Left atrial volume | * |
dc.subject | Mitral stenosis | * |
dc.subject | Prognosis | * |
dc.title | Prognostic implications of the left atrial volume index in patients with progressive mitral stenosis | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 27 | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 122 | * |
dc.relation.lastpage | 133 | * |
dc.relation.journaltitle | Journal of Cardiovascular Imaging | * |
dc.identifier.doi | 10.4250/jcvi.2019.27.e20 | * |
dc.identifier.scopusid | 2-s2.0-85068923075 | * |
dc.author.google | Cho I.-J. | * |
dc.author.google | Jeong H. | * |
dc.author.google | Choi J.-Y. | * |
dc.author.google | Lee S.-E. | * |
dc.author.google | Chang H.-J. | * |
dc.contributor.scopusid | 조인정(26537053500) | * |
dc.date.modifydate | 20240603130120 | * |