View : 467 Download: 0
Clinical features and prognosis of patients with idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease
- Title
- Clinical features and prognosis of patients with idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease
- Authors
- Lee, S. H.; Park, J. S.; Kim, S. Y.; Kim, D. S.; Kim, Y. W.; Chung, M. P.; Uh, S. T.; Park, C. S.; Park, S. W.; Jeong, S. H.; Park, Y. B.; Lee, H. L.; Shin, J. W.; Lee, J. H.; Jegal, Y.; Lee, H. K.; Kim, Y. H.; Song, J. W.; Park, M. S.
- Ewha Authors
- 이진화
- SCOPUS Author ID
- 이진화
- Issue Date
- 2019
- Journal Title
- INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- ISSN
- 1027-3719
1815-7920
- Citation
- INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE vol. 23, no. 6, pp. 678 - 684
- Keywords
- chronic obstructive pulmonary fibrosis; IPF; prognosis
- Publisher
- INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D)
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- BACKGROUND: Idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) share common risk factors. They could therefore be expressed in a single patient. However, the prevalence, clinical characteristics and prognosis of individuals with comorbid IPF and COPD are not known. METHOD: From 2003 to 2007, the Korean Interstitial Lung Disease Study Group created a register for idiopathic interstitial pneumonia using 2002 ATS/ERS (American Thoracic Society/European Respiratory Society) criteria. Of the 1546 IPF patients assessed, 143 had decreased lung function consistent with COPD (IPF-COPD). COPD was diagnosed based on age (>= 40 years) and pulmonary function (forced expiratory volume in 1 sec [FEV1]/forced vital capacity [FVC] ratio < 0.7). RESULTS : The median age of the IPF-COPD group was 71.0 years (interquartile range 66.0-76.0); most patients were male (88.1%). FVC (%) was significantly higher in the IPF-COPD group; however, FEV1 (%) was significantly lower in the IPF-COPD group (P < 0.001). Diffusing capacity of the lung for carbon monoxide (DLCO) was not significantly different between the two groups. In survival analysis, age and FVC (%), but not COPD, were significantly associated with prognosis (respectively P = 0.003, 0.001 and 0.401). COPD severity was also not related to prognosis (P = 0.935). CONCLUSION: The prevalence of IPF-COPD was estimated to be similar to 9.2% among all IPF patients; prognosis of patients with IPF-COPD was not worse than those with IPF alone.
- DOI
- 10.5588/ijtld.18.0194
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML