Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 송태진 | * |
dc.date.accessioned | 2020-08-13T16:30:23Z | - |
dc.date.available | 2020-08-13T16:30:23Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 2045-2322 | * |
dc.identifier.other | OAK-27300 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/254957 | - |
dc.description.abstract | Serum cardiac troponin I (cTnI) is often elevated in patients with ischemic stroke, and is associated with their prognosis. Since cTnI is also closely related to atrial fibrillation (AF), cTnI may be a sensitive prognostic indicator in patients with AF-related stroke. This study aimed to evaluate the association between serum cTnI and early neurological deterioration (END) in patients with AF-related stroke. We included consecutive AF-related stroke patients between 2013 and 2015. END was defined as an increase ≥ 2 in the total NIHSS score or ≥ 1 in the motor NIHSS score within the first 72 h of admission. A total of 1,133 patients with AF-related stroke were evaluated. In multivariable analysis, cTnI [adjusted odds ratio (aOR) = 1.16, 95% confidence interval (CI) 1.00–1.34; P = 0.047] remained significant after adjusting for confounders. Initial NIHSS score (aOR = 1.03, 95% CI 1.00–1.06; P = 0.043) was also positively associated with END; meanwhile, the use of anticoagulants was negatively associated in both vitamin K antagonists (aOR = 0.35, 95% CI 0.23–0.54; P < 0.001) and new oral anticoagulants (aOR = 0.41, 95% CI 0.19–0.89; P = 0.024). In conclusion, higher serum cTnI was associated with END in patients with AF-related stroke. © 2020, The Author(s). | * |
dc.language | English | * |
dc.publisher | Nature Research | * |
dc.title | Elevated troponin levels are associated with early neurological worsening in ischemic stroke with atrial fibrillation | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 10 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Scientific Reports | * |
dc.identifier.doi | 10.1038/s41598-020-69303-5 | * |
dc.identifier.wosid | WOS:000556400100016 | * |
dc.identifier.scopusid | 2-s2.0-85088636022 | * |
dc.author.google | Nam K.-W. | * |
dc.author.google | Kim C.K. | * |
dc.author.google | Yu S. | * |
dc.author.google | Chung J.-W. | * |
dc.author.google | Bang O.Y. | * |
dc.author.google | Kim G.-M. | * |
dc.author.google | Jung J.-M. | * |
dc.author.google | Song T.-J. | * |
dc.author.google | Kim Y.-J. | * |
dc.author.google | Kim B.J. | * |
dc.author.google | Heo S.H. | * |
dc.author.google | Park K.-Y. | * |
dc.author.google | Kim J.-M. | * |
dc.author.google | Park J.-H. | * |
dc.author.google | Choi J.C. | * |
dc.author.google | Park M.-S. | * |
dc.author.google | Kim J.-T. | * |
dc.author.google | Choi K.-H. | * |
dc.author.google | Hwang Y.H. | * |
dc.author.google | Seo W.-K. | * |
dc.author.google | Oh K. | * |
dc.contributor.scopusid | 송태진(55507164200) | * |
dc.date.modifydate | 20240304123954 | * |