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Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea
- Title
- Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea
- Authors
- Moon, Jung Rock; Lee, Chang Kyun; Hong, Sung Noh; Im, Jong Pil; Ye, Byong Duk; Cha, Jae Myung; Jung, Sung-Ae; Lee, Kang-Moon; Park, Dong Il; Jeen, Yoon Tae; Park, Young Sook; Cheon, Jae Hee; Kim, Hyesung; Seo, BoJeong; Kim, Youngdoe; Kim, Hyo Jong|KASID
- Ewha Authors
- 정성애
- SCOPUS Author ID
- 정성애
- Issue Date
- 2020
- Journal Title
- GUT AND LIVER
- ISSN
- 1976-2283
2005-1212
- Citation
- GUT AND LIVER vol. 14, no. 4, pp. 459 - 467
- Keywords
- Colitis; ulcerative; Patient reported outcome measures; Quality of life; Anxiety; Depression
- Publisher
- EDITORIAL OFFICE GUT &
LIVER
- Indexed
- SCIE; SCOPUS; KCI
- Document Type
- Article
- Abstract
- Background/Alms: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of life (HRQL) among patients newly diagnosed with moderate-to-severe UC who were affiliated with the nationwide prospective cohort study. Methods: Within the first 4 weeks of UC diagnosis, all patients were assessed using the Hospital Anxiety and Depression Scale (HADS), Work Productivity and Activity Impairment questionnaire, Inflammatory Bowel Disease Questionnaire (IBDQ), and 12-Item Short Form (SF-12) health survey. A multiple linear regression model was used to identify factors associated with HRQL. Results: Between August 2014 and February 2017, 355 patients completed questionnaires. Significant mood disorders requiring psychological interventions, defined by a HADS score >= 11, were identified in 16.7% (anxiety) and 20.6% (depression) of patients. Patients with severe disease were more likely to have presenteeism, loss of work productivity, and activity loss than those with moderate disease (all p<0.05). Significant mood disorders had the strongest negative relationship with total IBDQ score, which indicates disease-specific HRQL (beta coefficient: -22.1 for depression and -40.0 for anxiety, p<0.001). The scores of all SF-12 dimensions, which indicate general HRQL, were remarkably decreased in the study population compared indirectly with previously reported scores in the general population. The Mayo score, C-reactive protein level, and white blood cell count showed significant negative associations with the IBDQ score (p<0.05). Conclusions: Psychosocial screening and timely interventions should be incorporated into the initial care of patients newly diagnosed with UC.
- DOI
- 10.5009/gnl19107
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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