Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 정성애 | * |
dc.date.accessioned | 2020-05-25T16:30:09Z | - |
dc.date.available | 2020-05-25T16:30:09Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 1976-2283 | * |
dc.identifier.issn | 2005-1212 | * |
dc.identifier.other | OAK-26962 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/253914 | - |
dc.description.abstract | Background/Aims: A considerable number of patients with Crohn's disease still need intestinal resection surgery. Postoperative recurrence is an important issue in Crohn's disease management, including the selection of high-risk patients. Eastern Asian patients showed several differences from Caucasian patients. Therefore, we investigated the postoperative surgical recurrence outcome and identified risk factors in Korean patients. Methods: Clinical data of 372 patients with Crohn's disease who underwent first intestinal resection between January 2004 and August 2014 at 14 hospitals in Korea were retrospectively reviewed. Results: Over the follow-up period, 50 patients (17.1%) showed surgical recurrence. The cumulative surgical recurrence rate was 6.5% at 1 year and 15.4% at 7 years. Age under 16 (p=0.011; hazard ratio [HR], 5.136; 95% confidence interval [CI], 1576 to 16.731), colonic involvement (p=0.023; HR , 2.011; 95% CI, 1.102 to 3.670), and the presence of perianal disease at surgery (p=0.008; HR, 2.239; 95% CI, 1.236 to 4.059) were independent risk factors associated with surgical recurrence. Postoperative thiopurine treatment (p=0.002; HR, 0.393; 95% CI, 0.218 to 0.710) was a protective factor for surgical recurrence. Conclusions: Among the disease characteristics at surgery, younger age, colonic location, and perianal lesions were independent risk factors for surgical recurrence. Postoperative thiopurine treatment significantly reduced the incidence of surgical recurrence. | * |
dc.language | English | * |
dc.publisher | EDITORIAL OFFICE GUT & | * |
dc.publisher | LIVER | * |
dc.subject | Crohn disease | * |
dc.subject | Recurrence | * |
dc.subject | Surgery | * |
dc.subject | Risk factors | * |
dc.subject | Thiopurine | * |
dc.title | Risk Factors for Postoperative Recurrence in Korean Patients with Crohn's Disease | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 14 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 331 | * |
dc.relation.lastpage | 337 | * |
dc.relation.journaltitle | GUT AND LIVER | * |
dc.identifier.doi | 10.5009/gnl19085 | * |
dc.identifier.wosid | WOS:000533543100010 | * |
dc.identifier.scopusid | 2-s2.0-85084694307 | * |
dc.author.google | Kim, Sung | * |
dc.author.google | Cheon, Jae Hee | * |
dc.author.google | Park, Jae Jun | * |
dc.author.google | Kim, Eun Soo | * |
dc.author.google | Jeon, Seong Woo | * |
dc.author.google | Jung, Sung-Ae | * |
dc.author.google | Park, Dong Il | * |
dc.author.google | Lee, Chang Kyun | * |
dc.author.google | Im, Jong Pil | * |
dc.author.google | Kim, You Sun | * |
dc.author.google | Kim, Hyun Soo | * |
dc.author.google | Lee, Jun | * |
dc.author.google | Eun, Chang Soo | * |
dc.author.google | Lee, Jeong Mi | * |
dc.author.google | Jang, Byung Ik | * |
dc.author.google | Seo, Geom Seog | * |
dc.contributor.scopusid | 정성애(7403676915) | * |
dc.date.modifydate | 20240415140437 | * |