Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이진화 | * |
dc.date.accessioned | 2020-03-23T16:30:19Z | - |
dc.date.available | 2020-03-23T16:30:19Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 0954-6111 | * |
dc.identifier.other | OAK-26583 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/253619 | - |
dc.description.abstract | Background: Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of vitamin D deficiency. Vitamin D levels also correlate with lung function in patients with COPD. However, there are few reports on vitamin D deficiency and emphysema severity in COPD. This study aimed to investigate the effects of plasma 25-hydroxyvitamin D (25-OHD) level on emphysema severity in male COPD patients. Methods: A total of 151 male subjects were selected from the Korean Obstructive Lung Disease (KOLD) cohort. Subjects were subdivided into four subgroups according to their baseline plasma 25-OHD level: sufficiency (≥20 ng/ml), mild deficiency (15–20 ng/ml), moderate deficiency (10–15 ng/ml), and severe deficiency (<10 ng/ml). Results: Baseline computed tomography (CT) emphysema indices revealed significant differences among the subgroups (p = 0.034). A statistically significant difference was also observed among the subgroups regarding change in the CT emphysema index over 3 years (p = 0.047). The annual increase in emphysema index was more prominent in the severe deficiency group (1.34% per year) than in the other groups (0.41% per year) (p = 0.003). Conclusions: This study demonstrates that CT emphysema indices were different among the four subgroups and supports that severe vitamin D deficiency is associated with rapid progression of emphysema in male patients with COPD. © Elsevier Ltd | * |
dc.language | English | * |
dc.publisher | W.B. Saunders Ltd | * |
dc.subject | Chronic obstructive pulmonary disease | * |
dc.subject | Emphysema | * |
dc.subject | Vitamin D | * |
dc.title | Severe vitamin D deficiency is associated with emphysema progression in male patients with COPD | * |
dc.type | Article | * |
dc.relation.volume | 163 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Respiratory Medicine | * |
dc.identifier.doi | 10.1016/j.rmed.2020.105890 | * |
dc.identifier.wosid | WOS:000517519500003 | * |
dc.identifier.scopusid | 2-s2.0-85078889222 | * |
dc.author.google | Kim C. | * |
dc.author.google | Ko Y. | * |
dc.author.google | Jung J.Y. | * |
dc.author.google | Lee J.S. | * |
dc.author.google | Rhee C.K. | * |
dc.author.google | Lee J.H. | * |
dc.author.google | Lee J.-H. | * |
dc.author.google | Moon J.-Y. | * |
dc.author.google | Lim S.Y. | * |
dc.author.google | Yoo K.H. | * |
dc.author.google | Seo J.B. | * |
dc.author.google | Oh Y.-M. | * |
dc.author.google | Lee S.-D. | * |
dc.author.google | Park Y.B. | * |
dc.contributor.scopusid | 이진화(56646645800;58376333800) | * |
dc.date.modifydate | 20240419140935 | * |