Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안정훈 | * |
dc.date.accessioned | 2020-01-14T16:30:11Z | - |
dc.date.available | 2020-01-14T16:30:11Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 0039-2499 | * |
dc.identifier.issn | 1524-4628 | * |
dc.identifier.other | OAK-26254 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/252384 | - |
dc.description.abstract | Background and Purpose- The theory of cognitive reserve (CR) was introduced to account for individual differences in the clinical manifestation of neuropathology. This study investigated whether CR has a modulating effect on cognitive impairment and recovery after stroke. Methods- This study is an interim analysis of the Korean Stroke Cohort for Functioning and Rehabilitation. A total of 7459 patients with first-ever stroke were included for analysis. Education, occupation, and composite CR scores derived from those 2 variables were used as CR proxies. Scores from the Korean version of the Mini-Mental State Examination analyzed for 30 months after stroke onset were analyzed. Results- Lower CR increased the risk of cognitive impairment after stroke. The odds ratio was 1.89 (95% CI, 1.64-2.19) in patients with secondary education and 2.42 (95% CI, 2.03-2.90) in patients with primary education compared with patients with higher education. The odds ratio was 1.48 (95% CI, 1.23-1.98) in patients with a skilled manual occupation and 2.01 (95% CI, 1.42-2.83) in patients with a nonskilled manual occupation compared with patients with a managerial or professional occupation. In the multilevel model analysis, the Korean version of the Mini-Mental State Examination total score increased during the first 3 months (1.93 points per month) and then plateaued (0.02 point per month). The slopes were moderated by the level of education, occupation, and composite CR score: the higher the level of education, occupation, or CR score, the faster the recovery. In the older adult group, the Korean version of the Mini-Mental State Examination scores showed a long-term decline that was moderated by education level. Conclusions- Education and occupation can buffer an individual against cognitive impairment caused by stroke and promote rapid cognitive recovery early after stroke. In addition, higher education minimizes long-term cognitive decline after stroke, especially in older patients. | * |
dc.language | English | * |
dc.publisher | LIPPINCOTT WILLIAMS & | * |
dc.publisher | WILKINS | * |
dc.subject | cognitive dysfunction | * |
dc.subject | cognitive reserve | * |
dc.subject | education | * |
dc.subject | longitudinal studies | * |
dc.subject | occupation | * |
dc.subject | risk factors | * |
dc.subject | stroke | * |
dc.title | Effect of Cognitive Reserve on Risk of Cognitive Impairment and Recovery After Stroke The KOSCO Study | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 51 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 99 | * |
dc.relation.lastpage | 107 | * |
dc.relation.journaltitle | STROKE | * |
dc.identifier.doi | 10.1161/STROKEAHA.119.026829 | * |
dc.identifier.wosid | WOS:000504225600029 | * |
dc.identifier.scopusid | 2-s2.0-85077223090 | * |
dc.author.google | Shin, Minyoung | * |
dc.author.google | Sohn, Min Kyun | * |
dc.author.google | Lee, Jongmin | * |
dc.author.google | Kim, Deog Young | * |
dc.author.google | Lee, Sam-Gyu | * |
dc.author.google | Shin, Yong-Il | * |
dc.author.google | Oh, Gyung-Jae | * |
dc.author.google | Lee, Yang-Soo | * |
dc.author.google | Joo, Min Cheol | * |
dc.author.google | Han, Eun Young | * |
dc.author.google | Han, Junhee | * |
dc.author.google | Ahn, Jeonghoon | * |
dc.author.google | Chang, Won Hyuk | * |
dc.author.google | Shin, Min A. | * |
dc.author.google | Choi, Ji Yoo | * |
dc.author.google | Kang, Sung Hyun | * |
dc.author.google | Kim, Youngtaek | * |
dc.author.google | Kim, Yun-Hee | * |
dc.contributor.scopusid | 안정훈(8855402200) | * |
dc.date.modifydate | 20240222163415 | * |