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A simple decontamination procedure for unintended iodide impurity during [C-11]methionine production

Title
A simple decontamination procedure for unintended iodide impurity during [C-11]methionine production
Authors
Park, Hyun SikMoon, Byung SeokLee, Hong JinAn, Hyun HoKim, Bom SahnLee, Won WooKim, Sang EunLee, Byung Chul
Ewha Authors
김범산문병석
SCOPUS Author ID
김범산scopus
Issue Date
2019
Journal Title
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
ISSN
0236-5731JCR Link

1588-2780JCR Link
Citation
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY vol. 322, no. 2, pp. 933 - 939
Keywords
L-[S-methyl-C-11]methionineIodine impurity[C-11]RadiopharmaceuticalsAnion-exchange resin cartridge
Publisher
SPRINGER
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
A solid-phase extraction cartridge method is a widely used carbon-11 labeling method for obtaining [C-11]methionine. Although the process is convenient and efficient, unintended impurity sometimes observed in the final product owing to contamination by volatile iodide generated during [C-11]CH3I production. Herein, we suggest a simple method to eliminate impurities contained in [C-11]methionine solution using an anion-exchange resin cartridge.
DOI
10.1007/s10967-019-06757-6
Appears in Collections:
의료원 > 의료원 > Journal papers
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