View : 48 Download: 0

The clinical utility of transperineal templateguided saturation prostate biopsy for risk stratification after transrectal ultrasound-guided biopsy

Title
The clinical utility of transperineal templateguided saturation prostate biopsy for risk stratification after transrectal ultrasound-guided biopsy
Authors
Song W.Kang M.Jeong B.C.Seo S.I.Jeon S.S.Lee H.M.Jeon H.G.
Ewha Authors
송완
Issue Date
2019
Journal Title
Investigative and Clinical Urology
ISSN
2466-0493JCR Link
Citation
Investigative and Clinical Urology vol. 60, no. 6, pp. 454 - 462
Keywords
BiopsyProstatic neoplasmsRiskWatchful waiting
Publisher
Korean Urological Association
Indexed
SCIE; SCOPUS; KCI WOS scopus
Document Type
Article
Abstract
Purpose: To investigate the clinical utility of transperineal template-guided saturation prostate biopsy (TPB) for risk stratification after transrectal ultrasound (TRUS)-guided biopsy. Materials and Methods: We retrospectively reviewed 155 patients who underwent TPB after previously negative results on TRUSguided biopsy (n=58) or who were candidates for active surveillance (n=97) fulfilling the PRIAS criteria between May 2017 and November 2018. The patients’ clinicopathologic data were reviewed, and the detection of clinically significant cancer (CSC) and upgrading of Gleason grade were identified. Results: The patients’ median age and pre-TPB prostate-specific antigen (PSA) value were 65.0 years and 5.74 ng/mL, respectively. A median of 36 biopsy cores was obtained in each patient, with a median TPB core density of 0.88 cores/cm3. Of the 58 males with a previous negative result on TRUS-guided biopsy, prostate cancer (PCa) was detected in 17 males (29.3%), including 8 with CSC. Of the 97 patient candidates for active surveillance, upgrading of the Gleason grade was identified in 31 males (32.0%), 20 with a Gleason grade of 7 (3+4), 6 with a Gleason grade of 7 (4+3), and 5 with a Gleason grade of 8 (4+4). The overall complication rate was 14.8% (23/155), and there were no Clavien–Dindo grade 3 to 5 complications. Conclusions: TPB helps to stratify the risk of PCa that was previously missed or underdiagnosed by TRUS-guided biopsy. TPB might be used as a diagnostic tool to determine risk classification and to help counsel patients with regard to treatment decisions. © The Korean Urological Association.
DOI
10.4111/icu.2019.60.6.454
Appears in Collections:
ETC > ETC
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE