Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 홍근 | * |
dc.date.accessioned | 2019-11-22T16:30:18Z | - |
dc.date.available | 2019-11-22T16:30:18Z | - |
dc.date.issued | 2014 | * |
dc.identifier.issn | 0902-0063 | * |
dc.identifier.issn | 1399-0012 | * |
dc.identifier.other | OAK-25660 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/252216 | - |
dc.description.abstract | Non-alcoholic fatty liver disease (NAFLD) affects a substantial proportion of the world population, and its prevalence has been increasing. The study was aimed at evaluating the prevalence and peri-transplant risk factors for post-liver transplantation (LT) NAFLD. A retrospective review was performed for adult recipients who underwent late protocol biopsy (>1yr after LT) between August 2010 and December 2012. Hepatic steatosis was reviewed and graded by hepatopathologists, and the peri-transplant factors were analyzed for relationships to histologically proven NAFLD. Total 166 biopsies had been performed in 156 recipients. NAFLD was present in 27.1% at a mean period of 35.4months between LT and biopsy, moderate and severe steatosis (33%) consisted of 28.9%. In multivariate analysis, pre-LT alcoholic cirrhosis (odds ratio [OR] 8.031, p=0.003), obesity at biopsy (OR 3.873, p=0.001), and preexisting donor graft steatosis (OR 3.147, p=0.022) were significant risk factors for post-LT NAFLD. In conclusion, NAFLD represented a considerable portion of recipients, but this prevalence was not higher than those for general population. Three risk factors were significantly related to post-LT NAFLD, and recipients with those factors should be monitored for NAFLD. Furthermore, possible progression to non-alcoholic steatohepatitis (NASH) or fibrosis and metabolic syndrome should be considered in future studies. | * |
dc.language | English | * |
dc.publisher | WILEY | * |
dc.subject | biopsy | * |
dc.subject | hepatic steatosis | * |
dc.subject | histology | * |
dc.subject | steatohepatitis | * |
dc.subject | steatosis | * |
dc.subject | transplant | * |
dc.title | Histologically proven non- alcoholic fatty liver disease and clinically related factors in recipients after liver transplantation | * |
dc.type | Article | * |
dc.relation.issue | 5 | * |
dc.relation.volume | 28 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 521 | * |
dc.relation.lastpage | 529 | * |
dc.relation.journaltitle | CLINICAL TRANSPLANTATION | * |
dc.identifier.doi | 10.1111/ctr.12343 | * |
dc.identifier.wosid | WOS:000335388800001 | * |
dc.author.google | Kim, Hyeyoung | * |
dc.author.google | Lee, Kyoungbun | * |
dc.author.google | Lee, Kwang-Woong | * |
dc.author.google | Yi, Nam-Joon | * |
dc.author.google | Lee, Hae Won | * |
dc.author.google | Hong, Geun | * |
dc.author.google | Choi, YoungRok | * |
dc.author.google | You, Tae | * |
dc.author.google | Suh, Suk-Won | * |
dc.author.google | Jang, Ja June | * |
dc.author.google | Suh, Kyung-Suk | * |
dc.contributor.scopusid | 홍근(55558687200) | * |
dc.date.modifydate | 20240429131310 | * |