Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 홍근 | * |
dc.date.accessioned | 2019-11-22T16:30:06Z | - |
dc.date.available | 2019-11-22T16:30:06Z | - |
dc.date.issued | 2014 | * |
dc.identifier.issn | 0172-6390 | * |
dc.identifier.other | OAK-25718 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/252166 | - |
dc.description.abstract | Background/Aims: The C-reactive protein level has been reported as a prognostic predictor for hepatocellular carcinoma after surgery We investigated the usefulness of preoperative C-reactive protein levels in predicting outcomes after living donor liver transplantation for hepatocellular carcinoma and identified preoperative risk factors. Methodology: We retrospectively analyzed 96 hepatocellular carcinoma patients who underwent living donor liver transplantation in March 2003-November 2009. The effect of preoperative variables on overall survival was evaluated by multivariate analysis. Results: The 5-year overall survival rate was significantly lower for C-reactive protein levels >0.3mg/dL than for C-reactive protein levels <= 0.3mg/dL (55.8% vs. 89.8%; P=0.001). In multivariate analysis, C-reactive protein levels >0.3mg/dL (P=0.006) and alpha-fetoprotein levels >200ng/mL (P<0.001) were significant risk factors for survival. For patients within Milan criteria (n=68), the 3-year overall survival rate with 2 risk factors (n=8) was 20%; of these patients, 63% experienced recurrence. For patients outside Milan criteria (n=28), the 5-year overall survival rate without 1-2 risk factors (n=21) was 80.9%; of these patients, 33% experienced recurrence. Conclusions: Preoperative C-reactive protein levels predicted prognosis after living donor liver transplantation for hepatocellular carcinoma. C-reactive protein and alpha-fetoprotein levels together with Milan criteria may improve hepatocellular carcinoma patient selection for liver transplantation. | * |
dc.language | English | * |
dc.publisher | H G E UPDATE MEDICAL PUBLISHING S A | * |
dc.subject | Milan criteria | * |
dc.subject | Liver transplantation | * |
dc.subject | Inflammation | * |
dc.subject | C-reactive protein | * |
dc.subject | Alpha-fetoprotein | * |
dc.subject | Hepatocellular carcinoma | * |
dc.title | Usefulness of Preoperative C-Reactive Protein and Alpha-Fetoprotein Levels for Prognostication of Patients with Hepatocellular Carcinoma after Living Donor Liver Transplantation | * |
dc.type | Article | * |
dc.relation.issue | 136 | * |
dc.relation.volume | 61 | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 2353 | * |
dc.relation.lastpage | 2358 | * |
dc.relation.journaltitle | HEPATO-GASTROENTEROLOGY | * |
dc.identifier.doi | 10.5754/hge13322 | * |
dc.identifier.wosid | WOS:000346326500042 | * |
dc.author.google | Mori, Shozo | * |
dc.author.google | Choi, Youngrok | * |
dc.author.google | Park, Min-Su | * |
dc.author.google | Kim, Hyeyoung | * |
dc.author.google | Hong, Geun | * |
dc.author.google | Yi, Nam-Joon | * |
dc.author.google | Lee, Kwang-Woong | * |
dc.author.google | Suh, Kyung-Suk | * |
dc.contributor.scopusid | 홍근(55558687200) | * |
dc.date.modifydate | 20240429131310 | * |