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Combined Outer Volume Suppression and T-2 Preparation Sequence for Coronary Angiography

Title
Combined Outer Volume Suppression and T-2 Preparation Sequence for Coronary Angiography
Authors
Luo, JieyingAddy, Nii OkaiIngle, R. ReeveHargreaves, Brian A.Hu, Bob S.Nishimura, Dwight G.Shin, Taehoon
Ewha Authors
신태훈
Issue Date
2015
Journal Title
MAGNETIC RESONANCE IN MEDICINE
ISSN
0740-3194JCR Link

1522-2594JCR Link
Citation
MAGNETIC RESONANCE IN MEDICINE vol. 74, no. 6, pp. 1632 - 1639
Keywords
outer volume suppressionT-2 Prepcones imagingradiofrequency pulse designcoronary MR angiography
Publisher
WILEY-BLACKWELL
Indexed
SCI; SCIE; SCOPUS WOS
Document Type
Article
Abstract
Purpose: To develop a magnetization preparation sequence for simultaneous outer volume suppression (OVS) and T-2 weighting in whole-heart coronary magnetic resonance angiography. Methods: A combined OVS and T-2 preparation sequence (OVS-T-2 Prep) was designed with a nonselective adiabatic 90 degrees tipdown pulse, two adiabatic 180 degrees refocusing pulses, and a 2D spiral -90 degrees tipup pulse. The OVS-T-2 Prep preserves the magnetization inside an elliptic cylinder with T-2 weighting, while saturating the magnetization outside the cylinder. Its performance was tested on phantoms and on 13 normal subjects with coronary magnetic resonance angiography using 3D cones trajectories. Results: Phantom studies showed expected T-2-dependent signal amplitude in the spatial passband and suppressed signal in the spatial stopband. In vivo studies with full-field-of-view cones yielded a passband-to-stopband signal ratio of 3.18 +/- 0.77 and blood-myocardium contrast-to-noise ratio enhancement by a factor of 1.43 +/- 0.20 (P < 0.001). In vivo studies with reduced-field-of-view cones showed that OVS-T-2 Prep well suppressed the aliasing artifacts, as supported by significantly reduced signal in the regions with no tissues compared to the images acquired without preparation (P < 0.0001). Conclusion: OVS-T-2 Prep is a compact sequence that can accelerate coronary magnetic resonance angiography by suppressing signals from tissues surrounding the heart while simultaneously enhancing the blood-myocardium contrast. (C) 2014 Wiley Periodicals, Inc.
DOI
10.1002/mrm.25575
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엘텍공과대학 > 휴먼기계바이오공학부 > Journal papers
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