Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권형주 | * |
dc.date.accessioned | 2019-11-19T16:30:44Z | - |
dc.date.available | 2019-11-19T16:30:44Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 0025-7974 | * |
dc.identifier.issn | 1536-5964 | * |
dc.identifier.other | OAK-25879 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/251990 | - |
dc.description.abstract | We evaluated the association between weight change in middle-aged adults and papillary thyroid cancer (PTC) based on a large-scale case-control study. Our study included data from 1551 PTC patients (19.3% men and 80.7% women) who underwent thyroidectomy at the 3 general hospitals in Korea and 15,510 individually matched control subjects. The subjects' weight history, epidemiologic information, and tumor characteristics confirmed after thyroidectomy were analyzed. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were determined for the annual average changes in weight and obesity indicators (body mass index (BMI), body surface area, and body fat percentage (BF%) in subjects since the age of 35 years. Subjects with a total weight gain >= 10 kg after age 35 years were more likely to have PTC(men, OR, 5.39, 95% CI, 3.88-7.49; women, OR, 3.36, 95% CI, 2.87-3.93) compared with subjects with a stable weight (loss or gain <5 kg). A marked increase in BMI since age 35 years (annual average change of BMI >= 0.3 kg/m(2)/yr) was related to an elevated PTC risk, and the association was more pronounced for large-sized PTC risks (<1cm, OR, 2.34, 95% CI, 1.92-2.85; >= 1 cm, OR, 4.00, 95% CI, 2.91-5.49, P heterogeneity = 0.005) compared with low PTC risks. Weight gain and annual increases in obesity indicators in middle-aged adults may increase the risk of developing PTC. | * |
dc.language | English | * |
dc.publisher | LIPPINCOTT WILLIAMS & | * |
dc.publisher | WILKINS | * |
dc.title | Annual Average Changes in Adult Obesity as a Risk Factor for Papillary Thyroid Cancer A Large-Scale Case-Control Study | * |
dc.type | Article | * |
dc.relation.issue | 9 | * |
dc.relation.volume | 95 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | MEDICINE | * |
dc.identifier.doi | 10.1097/MD.0000000000002893 | * |
dc.identifier.wosid | WOS:000375208900013 | * |
dc.author.google | Hwang, Yunji | * |
dc.author.google | Lee, Kyu Eun | * |
dc.author.google | Park, Young Joo | * |
dc.author.google | Kim, Su-Jin | * |
dc.author.google | Kwon, Hyungju | * |
dc.author.google | Park, Do Joon | * |
dc.author.google | Cho, Belong | * |
dc.author.google | Choi, Ho-Chun | * |
dc.author.google | Kang, Daehee | * |
dc.author.google | Park, Sue K. | * |
dc.contributor.scopusid | 권형주(57189926616) | * |
dc.date.modifydate | 20240222164535 | * |