Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김용재 | * |
dc.contributor.author | 송태진 | * |
dc.date.accessioned | 2019-11-05T16:30:08Z | - |
dc.date.available | 2019-11-05T16:30:08Z | - |
dc.date.issued | 2019 | * |
dc.identifier.issn | 2077-0383 | * |
dc.identifier.other | OAK-25606 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/251742 | - |
dc.description.abstract | Background: We investigated the effect of D-dimer levels and efficacy of different antithrombotic therapies according to the baseline D-dimer levels on recurrent stroke in patients with atrial fibrillation (AF)-related stroke and atherosclerosis. Methods: We enrolled 1441 patients with AF-related stroke and atherosclerosis in this nationwide multicenter study. The primary outcome measure was the occurrence of recurrent ischemic stroke over a 3-year period. Results: High D-dimer levels (>= 2 mu g/mL) were significantly associated with higher risk of recurrent ischemic stroke (adjusted hazard ratio (HR), 1.80; 95% confidence interval (CI), 1.13-2.84; p = 0.012). The risk of recurrent stroke was similar between the anticoagulant and the antiplatelet groups in all subjects (adjusted HR, 0.78; 95% CI, 0.46-1.32; p = 0.369). However, in patients with high D-dimer levels (>= 2 mu g/mL), risk of recurrent stroke was significantly lower in the anticoagulant group than in the antiplatelet group (adjusted HR, 0.40; 95% CI, 0.18-0.87; p = 0.022). Conclusion: Our findings suggested that baseline D-dimer levels could be used as a risk assessment biomarker of recurrent stroke in patients with AF-related stroke and atherosclerosis. High D-dimer levels would facilitate the identification of patients who are more likely to benefit from anticoagulants to ensure secondary prevention of stroke. | * |
dc.language | English | * |
dc.publisher | MDPI | * |
dc.subject | atrial fibrillation | * |
dc.subject | d-dimer | * |
dc.subject | outcome | * |
dc.subject | ischemic stroke | * |
dc.subject | antithrombotics | * |
dc.title | Baseline D-Dimer Levels as a Risk Assessment Biomarker for Recurrent Stroke in Patients with Combined Atrial Fibrillation and Atherosclerosis | * |
dc.type | Article | * |
dc.relation.issue | 9 | * |
dc.relation.volume | 8 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | JOURNAL OF CLINICAL MEDICINE | * |
dc.identifier.doi | 10.3390/jcm8091457 | * |
dc.identifier.wosid | WOS:000489184200191 | * |
dc.author.google | Choi, Kang-Ho | * |
dc.author.google | Seo, Woo-Keun | * |
dc.author.google | Park, Man-Seok | * |
dc.author.google | Kim, Joon-Tae | * |
dc.author.google | Chung, Jong-Won | * |
dc.author.google | Bang, Oh Young | * |
dc.author.google | Kim, Geong-Moon | * |
dc.author.google | Song, Tae-Jin | * |
dc.author.google | Kim, Bum Joon | * |
dc.author.google | Heo, Sung Hyuk | * |
dc.author.google | Jung, Jin-Man | * |
dc.author.google | Oh, Kyungmi | * |
dc.author.google | Kim, Chi Kyung | * |
dc.author.google | Yu, Sungwook | * |
dc.author.google | Park, Kwang Yeol | * |
dc.author.google | Kim, Jeong-Min | * |
dc.author.google | Park, Jong-Ho | * |
dc.author.google | Choi, Jay Chol | * |
dc.author.google | Hwang, Yang-Ha | * |
dc.author.google | Kim, Yong-Jae | * |
dc.contributor.scopusid | 김용재(36910759200) | * |
dc.contributor.scopusid | 송태진(55507164200) | * |
dc.date.modifydate | 20240304123954 | * |