Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 송태진 | * |
dc.date.accessioned | 2019-11-05T16:30:05Z | - |
dc.date.available | 2019-11-05T16:30:05Z | - |
dc.date.issued | 2019 | * |
dc.identifier.issn | 1738-6586 | * |
dc.identifier.issn | 2005-5013 | * |
dc.identifier.other | OAK-25614 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/251734 | - |
dc.description.abstract | Background and Purpose The clinical implications of echocardiography findings for long-term outcomes in atrial fibrillation (AF)-related stroke patients are unknown. Methods This was a substudy of the Korean ATrial fibrillaTion EvaluatioN regisTry in Ischemic strOke patieNts (K-ATTENTION), which is a multicenter-based cohort comprising prospective stroke registries from 11 tertiary centers. Stroke survivors who underwent two-dimensional transthoracic echocardiography during hospitalization were enrolled. Echocardiography markers included the left-ventricle (LV) ejection fraction (LVEF), the left atrium diameter, and the ratio of the peak transmitral filling velocity to the mean mitral annular velocity during early diastole (E/e' ratio). LVEF was categorized into normal (>= 55%), mildly decreased (>40% and <55%), and severely decreased (<= 40%). The E/e' ratio associated with the LV filling pressure was categorized into normal (<8), borderline (>= 8 and <15), and elevated (>= 15). Kaplan-Meier and Cox regression analyses were performed for recurrent stroke, major adverse cardiac events, and all-cause death. Results This study finally included 1,947 patients. Over a median follow-up of 1.65 years (interquartile range, 0.42-2.87 years), the rates of recurrent stroke, major adverse cardiac events, and all-cause death were 35.1, 10.8, and 69.6 cases per 1,000 person-years, respectively. Multivariable analyses demonstrated that severely decreased LVEF was associated with a higher risks of major adverse cardiac events [hazard ratio (HR), 3.91; 95% confidence interval (CI), 1.58-9.69] and all-cause death (HR, 1.95; 95% CI, 1.23-3.10). The multivariable fractional polynomial plot indicated that recurrent stroke might be associated with a lower LVEF. Conclusions Severe LV systolic dysfunction could be a determinant of long-term outcomes in AF-related stroke. | * |
dc.language | English | * |
dc.publisher | KOREAN NEUROLOGICAL ASSOC | * |
dc.subject | atrial fibrillation | * |
dc.subject | stroke | * |
dc.subject | echocardiography | * |
dc.subject | outcomes | * |
dc.title | Long-Term Outcomes of Real-World Korean Patients with Atrial-Fibrillation-Related Stroke and Severely Decreased Ejection Fraction | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 15 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 545 | * |
dc.relation.lastpage | 554 | * |
dc.relation.journaltitle | JOURNAL OF CLINICAL NEUROLOGY | * |
dc.identifier.doi | 10.3988/jcn.2019.15.4.545 | * |
dc.identifier.wosid | WOS:000491217300016 | * |
dc.author.google | Jung, Jin-Man | * |
dc.author.google | Kim, Yong-Hyun | * |
dc.author.google | Yu, Sungwook | * |
dc.author.google | O, Kyungmi | * |
dc.author.google | Kim, Chi Kyung | * |
dc.author.google | Song, Tae-Jin | * |
dc.author.google | Kim, Yong-Jae | * |
dc.author.google | Kim, Bum Joon | * |
dc.author.google | Heo, Sung Hyuk | * |
dc.author.google | Park, Kwang-Yeol | * |
dc.author.google | Kim, Jeong-Min | * |
dc.author.google | Park, Jong-Ho | * |
dc.author.google | Choi, Jay Chol | * |
dc.author.google | Park, Man-Seok | * |
dc.author.google | Kim, Joon-Tae | * |
dc.author.google | Choi, Kang-Ho | * |
dc.author.google | Hwang, Yang-Ha | * |
dc.author.google | Chung, Jong-Won | * |
dc.author.google | Bang, Oh Young | * |
dc.author.google | Kim, Gyeong-moon | * |
dc.author.google | Seo, Woo-Keun | * |
dc.contributor.scopusid | 송태진(55507164200) | * |
dc.date.modifydate | 20240304123954 | * |