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Correlations between invasively measured aortic pressures and left ventricular end-diastolic pressure in patients undergoing coronary angiography

Title
Correlations between invasively measured aortic pressures and left ventricular end-diastolic pressure in patients undergoing coronary angiography
Authors
Kim K.-J.Kim H.-L.Kang D.-Y.Park S.-H.Lim W.-H.Seo J.-B.Kim S.-H.Zo J.-H.Kim M.-A.
Ewha Authors
김경진
Issue Date
2019
Journal Title
Blood pressure monitoring
ISSN
1473-5725JCR Link
Citation
Blood pressure monitoring vol. 24, no. 5, pp. 241 - 247
Publisher
NLM (Medline)
Indexed
SCIE; SCOPUS scopus
Document Type
Article
Abstract
OBJECTIVE: Data on ventricular-arterial coupling using invasive hemodynamic studies are limited. This study was performed to clarify the interaction between aortic pressures and left ventricular end-diastolic pressure (LVEDP) using invasive catheterization. PATIENTS AND METHODS: A total of 104 consecutive stable patients (mean age, 65.8 ± 10.0 years; 56% men) undergoing invasive coronary angiography (ICA) were prospectively evaluated. LVEDP and central aortic pressures [systolic blood pressure (aSBP) and diastolic blood pressure (aDBP)] were sequentially measured using a pigtail catheter before ICA. Aortic pulse pressure (aPP) was defined by the difference between aSBP and aDBP. RESULTS: A total of 82 patients (79%) had obstructive coronary artery disease (≥50% stenosis). The mean LVEDP value was 18.7 ± 6.4 mmHg. Univariable analyses showed that aSBP (r = 0.309, P = 0.001) and aPP (r = 0.286, P = 0.003) significantly correlated with LVEDP, whereas aDBP was not correlated with LVEDP (P > 0.05). Multivariable analysis revealed that aSBP (β = 0.345, P = 0.001) and aPP (β = 0.276, P = 0.018) remained independent predictors of LVEDP even after controlling for potential confounders. CONCLUSION: Invasively measured aSBP and aPP were independently associated with invasively measured LVEDP in patients undergoing ICA. This result provides additional evidence of a close interaction between central aortic pressure and LV diastolic function in this population.
DOI
10.1097/MBP.0000000000000399
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의료원 > 의료원 > Journal papers
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