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A two-photon fluorescent probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues
- Title
- A two-photon fluorescent probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues
- Authors
- Chen, Liyan; Park, Sang Jun; Wu, Di; Kim, Hwan Myung; Yoon, Juyoung
- Ewha Authors
- 윤주영
- SCOPUS Author ID
- 윤주영
- Issue Date
- 2019
- Journal Title
- CHEMICAL COMMUNICATIONS
- ISSN
- 1359-7345
1364-548X
- Citation
- CHEMICAL COMMUNICATIONS vol. 55, no. 12, pp. 1766 - 1769
- Publisher
- ROYAL SOC CHEMISTRY
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Owing to the extreme toxicity of mercury, methods for its selective and sensitive sensing in solutions, and in live cells and tissues are in great demand. In this study, we developed a naphthalimide-based diphenylphosphinothioyl group-containing fluorescent and colorimetric probe that selectively detects mercury (Hg2+). Upon addition of mercury (Hg2+) to a solution of the probe, both a colorimetric change from colorless to yellow and a fluorescence change from blue to green (under a 365 nm hand-held UV lamp) occur, both of which can be observed using the "naked-eye". Furthermore, the probe possesses the capability of sensing intracellular mercury in both live cells and tissues using dual-emission channels and twophoton microscopy.
- DOI
- 10.1039/c8cc08608g
- Appears in Collections:
- 자연과학대학 > 화학·나노과학전공 > Journal papers
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