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Histological features of intracranial thrombi in stroke patients with cancer

Title
Histological features of intracranial thrombi in stroke patients with cancer
Authors
Park H.Kim J.Ha J.Hwang I.G.Song T.-J.Yoo J.Ahn S.H.Kim K.Kim B.M.Kim D.J.Kim Y.D.Nam H.S.Kwon I.Choi H.-J.Sohn S.-I.Lee H.S.Heo J.H.
Ewha Authors
송태진
SCOPUS Author ID
송태진scopus
Issue Date
2019
Journal Title
Annals of Neurology
ISSN
0364-5134JCR Link
Citation
Annals of Neurology vol. 86, no. 1, pp. 143 - 149
Publisher
John Wiley and Sons Inc.
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
The histological features of thrombus in stroke patients with cancer are not well known. Using immunohistochemical staining of thrombi retrieved during mechanical thrombectomy in stroke patients, thrombus compositions were compared between 16 patients with active cancer, 16 patients with inactive cancer, and 16 patients without any history of cancer. The active cancer group showed higher platelet and lower erythrocyte fractions than the inactive cancer or the control group. Four patients with vegetation showed very high platelet and low erythrocyte fractions. Patients with cryptogenic etiology in the active cancer group showed a similar pattern to those with vegetation. These findings may aid the determination of treatment strategies in cancer-associated stroke. ANN NEUROL 2019. © 2019 American Neurological Association
DOI
10.1002/ana.25495
Appears in Collections:
의과대학 > 의학과 > Journal papers
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