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Simple and rapid detection of bisphenol A using a gold nanoparticle-based colorimetric aptasensor

Title
Simple and rapid detection of bisphenol A using a gold nanoparticle-based colorimetric aptasensor
Authors
Lee E.-H.Lee S.K.Kim M.J.Lee S.-W.
Ewha Authors
이은희
SCOPUS Author ID
이은희scopusscopus
Issue Date
2019
Journal Title
Food Chemistry
ISSN
0308-8146JCR Link
Citation
Food Chemistry vol. 287, pp. 205 - 213
Keywords
AptamerBiosensorBisphenol AEndocrine disruptorGold nanoparticlesRice grain
Publisher
Elsevier Ltd
Indexed
SCI; SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
A colorimetric aptasensor was developed for the simple and rapid detection of bisphenol A (BPA). The aptasensor was designed to consist of colloidal gold nanoparticles (AuNPs) and a BPA-specific 24-bp aptamer. The AuNP-aptamer conjugates underwent an electrolyte-induced aggregation in the presence of sub-ppb levels of BPA. The surface plasmon resonance shift of AuNPs facilitated a color change from red to blue upon aggregation, which was visually observed by the naked eye. The corresponding visual limit of detection of BPA was as low as 1 pg/mL (0.004 nM). The aptasensor also achieved a selective detection of BPA over a variety of BPA analogs. The applicability of the aptasensor was verified via a successful detection of BPA in a single grain of rice. This result indicates that the colorimetric aptasensor can be used in a screening procedure for food and environmental monitoring, with reliable performance to sub-ppb levels of BPA detection. © 2019 Elsevier Ltd
DOI
10.1016/j.foodchem.2019.02.079
Appears in Collections:
엘텍공과대학 > 환경공학전공 > Journal papers
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