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Increased risk of postoperative complications after total thyroidectomy with Graves' disease

Title
Increased risk of postoperative complications after total thyroidectomy with Graves' disease
Authors
Kwon H.Kim J.-K.Lim W.Moon B.-I.Paik N.S.
Ewha Authors
문병인임우성백남선권형주
SCOPUS Author ID
문병인scopus; 임우성scopus; 백남선scopus; 권형주scopus
Issue Date
2019
Journal Title
Head and Neck
ISSN
1043-3074JCR Link
Citation
Head and Neck vol. 41, no. 2, pp. 281 - 285
Keywords
complicationsGraves&aposdiseasehypoparathyroidismRLN injurythyroidectomy
Publisher
John Wiley and Sons Inc.
Indexed
SCI; SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Background: The effect of Graves' disease on the risk of postoperative complications in patients undergoing total thyroidectomy is unclear. Methods: The incidence of recurrent laryngeal nerve (RLN) injury and hypoparathyroidism were analyzed between 165 patients with Graves' disease (GD group) and 1:1 matched patients with euthyroid states (control group). Results: The matched cohorts did not differ in age, sex, body mass index, pathologic diagnosis, and extent of operation. Excised thyroid weight was higher in the Graves' disease than in the control group (60.1 g vs 22.6 g; P <.001). Multivariate analysis showed that Graves' disease significantly increased risks of transient RLN injury (odds ratio [OR] = 4.7, 95% confidence interval [CI] = 1.5-15.5; P =.010) and transient hypoparathyroidism (OR = 2.8, 95% CI = 1.3-5.8; P =.007). Rates of permanent complications were comparable in the Graves' disease and control groups. Conclusions: Graves' disease can be a predictive factor for postoperative RLN injury and hypoparathyroidism after total thyroidectomy. © 2018 Wiley Periodicals, Inc.
DOI
10.1002/hed.25484
Appears in Collections:
의과대학 > 의학과 > Journal papers
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