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Cost-utility analysis of the National Health Screening Program for chronic kidney disease in Korea

Title
Cost-utility analysis of the National Health Screening Program for chronic kidney disease in Korea
Authors
Go D.-S.Kim S.-H.Park J.Ryu D.-R.Lee H.-J.Jo M.-W.
Ewha Authors
류동열
SCOPUS Author ID
류동열scopus
Issue Date
2019
Journal Title
Nephrology
ISSN
1320-5358JCR Link
Citation
Nephrology vol. 24, no. 1, pp. 56 - 64
Keywords
chronic kidney diseasecost-effectivenesscost-utility analysisscreening
Publisher
Blackwell Publishing
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Aim: Although a National Health Screening Program (NHSP) for chronic kidney disease (CKD) has been implemented in Korea since 2002, its cost-effectiveness has never been determined. This study aimed to estimate the cost-utility of NHSP for CKD in Korea. Methods: A Markov decision analytic model was constructed to compare CKD screening strategies of the NHSP with no screening. We developed a model that simulated disease progression in a cohort aged 20–120 years or death from the societal perspective. Results: Biannual screening starting at age 40 for CKD by proteinuria (dipstick) and estimated glomerular filtration ratio had an ICUR of $66 874/QALY relative to no screening. The targeted screening strategy had an ICUR of $37 812/QALY and $40 787/QALY for persons with diabetes and hypertension, respectively. ICURs improved with lower cost strategies. The most influential parameter that might make screening more cost-effective was the effectiveness of treatment on CKD to decrease disease progression and mortality. Conclusions: The Korean NHSP for CKD is more cost-effective for patients with diabetes or hypertension than the general population, consistent with prior studies. Although it is too early to conclude the cost-effectiveness of the Korean NHSP for CKD, this study provides evidence that is useful in evaluating the cost-effectiveness of CKD interventions. © 2017 Asian Pacific Society of Nephrology
DOI
10.1111/nep.13203
Appears in Collections:
의과대학 > 의학과 > Journal papers
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