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dc.contributor.author정순섭-
dc.date.accessioned2019-01-02T16:30:26Z-
dc.date.available2019-01-02T16:30:26Z-
dc.date.issued2018-
dc.identifier.issn1306-696X-
dc.identifier.otherOAK-23961-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/248124-
dc.description.abstractBACKGROUND: We evaluated the feasibility of chitosan-coated sutures for intestinal anastomosis strength through wound-healing effect. METHODS: Vicryl and PDS sutures were coated with 2% chitosan. While laparotomy was applied to the first group, chitosan was applied in the peritoneal cavity in the second group. Then the following materials were applied to colon anastomosis, in order: Vicryl, PDS, chitosan-coated Vicryl, and chitosan-coated PDS sutures. On the 7th and 14th days, eight rats from each group were euthanized. RESULTS: The adhesion scores of chitosan and control groups were lower than the suture groups. The vascularization of Vicryl-chitosan was lower than PDS-chitosan on the 14th day (p=0.038). Fibroblast cells and vascularization of anastomosis with chitosan-coated Vicryl were lower than Vicryl and chitosan-coated PDS on the 14th day (p<0.05). The tensile strength of Vicryl-chitosan increased more than Vicryl in vitro (p<0.05) on the 14th and 7th days, but there was no difference in vivo. The tensile strength of PDS-chitosan decreased more than PDS on the 7th day in vivo (p<0.05). CONCLUSION: The chitosan-coating effect on the adhesion and reinforcement of anastomosis in some parts of Vicryl in vitro and PDS in vivo was slightly improved.-
dc.languageEnglish-
dc.publisherTURKISH ASSOC TRAUMA EMERGENCY SURGERY-
dc.subjectAnastomosis-
dc.subjectchitosan-
dc.subjectPDS suture-
dc.subjecttensile strength-
dc.subjectVicryl suture-
dc.subjectwound healing-
dc.titleEffect of chitosan coating on surgical sutures to strengthen the colonic anastomosis-
dc.typeArticle-
dc.relation.issue5-
dc.relation.volume24-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage405-
dc.relation.lastpage411-
dc.relation.journaltitleULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY-
dc.identifier.doi10.5505/tjtes.2018.59280-
dc.identifier.wosidWOS:000446506600005-
dc.author.googleAltinel, Yuksel-
dc.author.googleChung, Soon Soup-
dc.author.googleOkay, Guven-
dc.author.googleUgras, Nesrin-
dc.author.googleIsik, Ahmet Fatih-
dc.author.googleOzturk, Ersin-
dc.author.googleOzguc, Halil-
dc.contributor.scopusid정순섭(7404293115)-
dc.date.modifydate20190102143000-
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의과대학 > 의학과 > Journal papers
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