Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 편욱범 | * |
dc.contributor.author | 류동열 | * |
dc.date.accessioned | 2019-01-02T16:30:22Z | - |
dc.date.available | 2019-01-02T16:30:22Z | - |
dc.date.issued | 2018 | * |
dc.identifier.issn | 0194-911X | * |
dc.identifier.issn | 1524-4563 | * |
dc.identifier.other | OAK-23982 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/248105 | - |
dc.description.abstract | Evidence about the benefits of treating uncomplicated, low-risk, stage-1 hypertension is lacking. The study aimed to investigate the association between mean blood pressure (BP) and clinical outcomes, and to determine optimal BPs in treated, low-risk, stage-1 hypertension. From the National Health Insurance Service Health Examination Database, patients with stage-1 hypertension between 2005 and 2006 were selected. They had a systolic BP of 140 to 159 mmHg or diastolic BP of 90 to 99 mmHg. Patients were grouped as controlled (mean BP <140/90 mmHg; n=99301) and uncontrolled (mean BP 140/90 mmHg; n=49460) according to their mean BP recorded during the follow-up health examination. All-cause mortality and cardiovascular outcomes were examined. Mean BPs in the controlled and uncontrolled groups were 131.1/80.9 and 144.6/86.8 mmHg, respectively. Controlled BP was associated with significantly lower risks of all-cause mortality, all stroke, hemorrhagic stroke, ischemic stroke, and end-stage renal disease. Subgroup analysis demonstrated benefits of controlled BP in hypertensive patients aged <50 years for all-cause mortality, all stroke, hemorrhagic stroke, ischemic stroke, and end-stage renal disease, with no significant interaction according to age. The BP associated with the lowest risk of all-cause mortality was 120 to <130 mmHg (systolic BP) and 70 to <80 mmHg (diastolic BP). There was an increased risk of myocardial infarction in patients with mean systolic BP <120 mmHg and diastolic BP <80 mmHg. BP <140/90 mmHg was associated with a significant reduction in the risk of mortality, stroke, and end-stage renal disease, with the lowest mortality risk at BP ranges of 120 to <130 and 70 to <80 mmHg. | * |
dc.language | English | * |
dc.publisher | LIPPINCOTT WILLIAMS & | * |
dc.publisher | WILKINS | * |
dc.subject | blood pressure | * |
dc.subject | hypertension | * |
dc.subject | mortality | * |
dc.subject | myocardial infarction | * |
dc.subject | stroke | * |
dc.title | Clinical Benefit of Treatment of Stage-1, Low-Risk Hypertension: Korean National Health Insurance Database Analysis | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 72 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1285 | * |
dc.relation.lastpage | 1293 | * |
dc.relation.journaltitle | HYPERTENSION | * |
dc.identifier.doi | 10.1161/HYPERTENSIONAHA.118.11787 | * |
dc.identifier.wosid | WOS:000449404600011 | * |
dc.author.google | Lee, Chan Joo | * |
dc.author.google | Ryu, Jiin | * |
dc.author.google | Kim, Hyeon-Chang | * |
dc.author.google | Ryu, Dong-Ryeol | * |
dc.author.google | Ihm, Sang-Hyun | * |
dc.author.google | Kim, Yong-Jin | * |
dc.author.google | Shin, Jin-Ho | * |
dc.author.google | Pyun, Wook Bum | * |
dc.author.google | Kang, Hyoung-Soo | * |
dc.author.google | Park, Jong-Heon | * |
dc.author.google | Hwang, Jinseub | * |
dc.author.google | Park, Sungha | * |
dc.contributor.scopusid | 편욱범(6508352922) | * |
dc.contributor.scopusid | 류동열(7103144218;56997547400;56669926200) | * |
dc.date.modifydate | 20240123092816 | * |