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Demographic and clinical features of hidradenitis suppurativa in Korea

Title
Demographic and clinical features of hidradenitis suppurativa in Korea
Authors
Yang, Ji HoonMoon, JungyoonKye, Young ChulKim, Kwang JoongKim, Myeung NamRo, Young SuckPark, Mi YounAhn, Hyo HyunLee, Mi WooLee, Weon JuLee, Ju HeeLee, Jee BumJang, Min SooChoi, Yu SungChoi, You WonSuh, Dae HunKorean Soc Acne Res
Ewha Authors
최유원
SCOPUS Author ID
최유원scopus
Issue Date
2018
Journal Title
JOURNAL OF DERMATOLOGY
ISSN
0385-2407JCR Link

1346-8138JCR Link
Citation
JOURNAL OF DERMATOLOGY vol. 45, no. 12, pp. 1389 - 1395
Keywords
Asiaepidemiologyhidradenitis suppurativaseveritytreatment
Publisher
WILEY
Indexed
SCIE; SCOPUS WOS
Document Type
Article
Abstract
Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disorder. Although several epidemiological studies have been conducted in Western countries, such data regarding Asian populations are scarce. In this study, we sought to investigate the demographic and clinical features of HS in Korea. A total of 438 patients, diagnosed with HS from May 2007 to April 2017, were enrolled and the electronic medical record of each patient was reviewed. Male patients were predominant with a male : female ratio of 2.5:1. Mean age of disease onset was 23.9 years and most patients had no family history. The most frequently affected area was the buttocks, followed by axillae and groin. Acne and diabetes mellitus were the most prevalent associated diseases and no patients with inflammatory bowel diseases were observed. In the univariable analysis, male patients had severe diseases compared with females with an odds ratio (OR) of 1.790. Two or more affected body regions were associated with HS severity with an OR of 1.693. While involvement of the perineum (OR, 4.067) and buttocks (OR, 1.471) tended to be associated with increased severity of the disease, the inguinal area (OR, 0.620) showed a tendency to be inversely associated with the severity. In multivariable analysis, identified risk factors were the involvement of the perineum (OR, 3.819) and buttocks (OR, 2.288). Smoking status and high body mass index seemed to be associated with more severe diseases. Our results will provide clinical characteristics of HS patients in Asia and help to broaden understanding of HS.
DOI
10.1111/1346-8138.14656
Appears in Collections:
의과대학 > 의학과 > Journal papers
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