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UVA blocking effect of epidermal melanin in patients with vitiligo

Title
UVA blocking effect of epidermal melanin in patients with vitiligo
Authors
Lee H.R.Kang H.C.Hahm J.H.
Ewha Authors
함정희강형철
Issue Date
1995
Journal Title
Annals of Dermatology
ISSN
1013-9087JCR Link
Citation
Annals of Dermatology vol. 7, no. 3, pp. 222 - 226
Indexed
SCIE; SCOPUS; KCI scopus
Document Type
Article
Abstract
Background: Ultraviolet light induces sunburn, aging of the skin, disorders of pigment and even promotes skin cancers. Melanin is known to have a protecting role in the skin by blocking ultraviolet light. Objective: The purpose of this study was to evaluate UVA blocking effect of epidermal melanin and to compare UVA blocking effect among different anatomical sites. Method: From 20 vitiligo patients who had undergone an epidermal graft, we obtained epidermis of normal and vitiliginous skin and measured transmitted UVA energy density. Results: The vitiliginous epidermis, devoid of melanin, blocked lower amount of UVA energy than the normal epidermis. 11.6% of irradiated UVA energy was blocked by epidermal melanin. No significant differences were observed in UVA blocking effect among different anatomical sites in-normal and vitiliginous epidermis. Conclusion: Epidermal melanin has some UVA blocking effect. No significant differences were found in UVA blocking effect among different anatomical sites despite the differences in the density of melanin pigment among different sites of the body.
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의과대학 > 의학과 > Journal papers
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