Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 신명헌 | - |
dc.date.accessioned | 2018-12-27T16:30:07Z | - |
dc.date.available | 2018-12-27T16:30:07Z | - |
dc.date.issued | 1996 | - |
dc.identifier.issn | 0023-4001 | - |
dc.identifier.other | OAK-16956 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/247974 | - |
dc.description.abstract | The TH cytokine responses of spleen cells stimulated with Con A from mice infected with Paragonimus westermani were examined. The spleen cell culture supernatants were assayed for TH1-specific IFN-gamma and TH2-specific IL-4. Cytokine responses for IL-4 peaked at three days (410 +/- 60.9 pg/ml), persisted at a high level until the second week (343 +/- 59.0 pg/ml), and then decreased slowly four and six weeks after infection. IFN-gamma production by splenocytes only increased during the first week (151 +/- 32.3 pg/ml) and declined abruptly after the second week of infection. IFN-gamma production by splenocytes of infected mice was not observed during the sixth week of infection. In addition, serum IL-4 and IFN-gamma were measured. Serum IL-4 was not detected in substantial quantity until four to six weeks after infection. The time course of serum IL-4 was not correlated with that of IL-4 production by splenocytes. Serum IFN-gamma was undetectable during the entire course of infection. These results suggest that TH2 cytokine responses, rather than TH1, predominate in mice infected with P. westermani. | - |
dc.language | English | - |
dc.title | Production of interferon-gamma and interleukin-4 by splenocytes in mice infected with Paragonimus westermani. | - |
dc.type | Article | - |
dc.relation.issue | 3 | - |
dc.relation.volume | 34 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 185 | - |
dc.relation.lastpage | 189 | - |
dc.relation.journaltitle | The Korean journal of parasitology | - |
dc.identifier.scopusid | 2-s2.0-0030237420 | - |
dc.author.google | Shin M.H. | - |
dc.author.google | Min D.Y. | - |
dc.date.modifydate | 20200911081002 | - |