Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 함정희 | - |
dc.date.accessioned | 2018-12-27T16:30:04Z | - |
dc.date.available | 2018-12-27T16:30:04Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0494-4739 | - |
dc.identifier.other | OAK-17161 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/247954 | - |
dc.description.abstract | Systemic PUVA therapy can produce various acute reactions and potential long-term damage including benign and malignant skin tumors. Obviously the risk is related to DNA damage, but PUVA-induced down-regulation of immune responses may play an additional role. Keratoacanthoma is etiologically related to sunlight and immunosuppression. PUVA keratoses are raised warty papules with a broad base and a diameter of several millimeters to 1 centimeter, and they are associated with an increased risk of nonmelanoma skin cancer. We report a case of solitary keratoacanthoma and multiple PUVA keratoses all developing in vitiliginous areas in a patient receiving long-term, high-dose PUVA therapy for generalized vitiligo. A 57-year-old Korean female, who had undergone intermittent systemic PUVA therapy for 11 years, noted multiple asymptomatic, yellowish, hyperkeratotic papules on the dorsa of hands and feet 1 year previously, and a bean-sized raised painful nodule filled with keratin plug on the dorsum of right hand 1 month previously. Skin biopsy confirmed the diagnoses of PUVA keratoses and keratoacanthoma, respectively. PCR-SSCP analysis revealed no mutation of p53 tumor suppressor gene in this case. | - |
dc.language | Korean | - |
dc.title | Keratoacanthoma and PUVA keratoses in a vitiligo patient following oral psoralen photochemotherapy (PUVA) | - |
dc.type | Article | - |
dc.relation.issue | 9 | - |
dc.relation.volume | 38 | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 1234 | - |
dc.relation.lastpage | 1238 | - |
dc.relation.journaltitle | Korean Journal of Dermatology | - |
dc.identifier.scopusid | 2-s2.0-0033774157 | - |
dc.author.google | Kim S.-H. | - |
dc.author.google | Kang M.-J. | - |
dc.author.google | Cho S. | - |
dc.author.google | Whang K.-K. | - |
dc.author.google | Hahln J.-H. | - |
dc.date.modifydate | 20181227103012 | - |