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The J-shape association of serum total IgE levels with age-related cataract

Title
The J-shape association of serum total IgE levels with age-related cataract
Authors
Park S.Choi N.-K.
Ewha Authors
최남경
Issue Date
2018
Journal Title
International Journal of Ophthalmology
ISSN
2222-3959JCR Link
Citation
International Journal of Ophthalmology vol. 11, no. 6, pp. 1009 - 1012
Keywords
AllergyCataractEyeIge
Publisher
International Journal of Ophthalmology (c/o Editorial Office)
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
● AIM: To address the association between serum total IgE levels and age-related cataract in adults. ● METHODS: The study participants consisted of 1052 adults aged 40y or older in the Korean National Health and Nutrition Examination Survey 2010. We performed multivariable logistic regression analyses using the quartile cut-points of total IgE levels. ● RESULTS: The odds ratios (ORs) for nuclear and any cataract with ≥267 kU/L of serum IgE levels were 1.75 [95% confidence intervals (CI), 1.04-2.96] and 2.00 (95%CI, 1.22-3.27), respectively, comparing to 35-87 kU/L. Interestingly, participants with ≤35 kU/L of IgE levels (OR, 1.67; 95%CI, 1.02-2.72) also had higher risk for any cataract than those with 35-87 kU/L. The risk for any cataract (OR, 1.48; 95%CI, 1.03-2.13) was higher in participants with high total IgE levels (>150 kU/L), comparing to normal participants. ● CONCLUSION: Our findings indicate a J-shaped relationship between serum IgE levels and age-related cataract. © 2018, International Journal of Ophthalmology (c/o Editorial Office). All rights reserved.
DOI
10.18240/ijo.2018.06.19
Appears in Collections:
신산업융합대학 > 융합보건학과 > Journal papers
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