Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상기 | * |
dc.date.accessioned | 2018-12-14T16:30:25Z | - |
dc.date.available | 2018-12-14T16:30:25Z | - |
dc.date.issued | 2018 | * |
dc.identifier.issn | 2155-5435 | * |
dc.identifier.other | OAK-22878 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/247581 | - |
dc.description.abstract | A straightforward route toward construction of a-quaternary chiral beta-lactam moiety via Rh(II)/Pd(0)-catalyzed stereoselective relay catalytic reaction is reported. This asymmetric dual relay catalysis involves Rh(II)-catalyzed enantioselective intramoluecular C-H insertions of alpha-diazoamides, and sequential Pd(0)-catalyzed diastereoselective intermolecular allylic alkylation. Under mild reaction conditions, a broad range of a-quaternary allylated chiral beta-lactams have been synthesized in high yields (up to 99%) with excellent stereoselectivities [up to diastereomeric ratio (dr) >99:1, up to 98% enantiomeric excess (ee)]. | * |
dc.language | English | * |
dc.publisher | AMER CHEMICAL SOC | * |
dc.subject | beta-lactam | * |
dc.subject | rhodium | * |
dc.subject | palladium | * |
dc.subject | C-H insertion | * |
dc.subject | allylic alkylation | * |
dc.subject | asymmetric catalysis | * |
dc.title | Asymmetric Rh(II)/Pd(0) Relay Catalysis: Synthesis of alpha-Quaternary Chiral beta-Lactams through Enantioselective C-H Insertion/Diastereoselective Allylation of Diazoamides | * |
dc.type | Article | * |
dc.relation.issue | 8 | * |
dc.relation.volume | 8 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 7340 | * |
dc.relation.lastpage | 7345 | * |
dc.relation.journaltitle | ACS CATALYSIS | * |
dc.identifier.doi | 10.1021/acscatal.8b01687 | * |
dc.identifier.wosid | WOS:000441112400053 | * |
dc.identifier.scopusid | 2-s2.0-85049316996 | * |
dc.author.google | Huang, Liang-Zhu | * |
dc.author.google | Xuan, Zi | * |
dc.author.google | Jeon, Hyun Ji | * |
dc.author.google | Du, Zhen-Ting | * |
dc.author.google | Kim, Ju Hyun | * |
dc.author.google | Lee, Sang-gi | * |
dc.contributor.scopusid | 이상기(15082786300) | * |
dc.date.modifydate | 20240123104103 | * |