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dc.contributor.author서주영-
dc.date.accessioned2018-12-07T16:30:28Z-
dc.date.available2018-12-07T16:30:28Z-
dc.date.issued2017-
dc.identifier.issn1598-2629-
dc.identifier.otherOAK-21236-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/247320-
dc.description.abstractEosinophils are potent effector cells implicated in allergic responses and helminth infections. Responding to stimuli, they release their granule-derived cytotoxic proteins and are involved in inflammatory processes. However, under homeostatic conditions, eosinophils are abundantly present in the intestine and are constantly in contact with the gut microbiota and maintain the balance of immune responses without inflammation. This situation indicates that intestinal eosinophils have an anti-inflammatory function unlike allergic eosinophils. In support of this notion, some papers have shown that eosinophils have different phenotypes depending on the site of residence and are a heterogeneous cell population. Recently, it was reported that eosinophils in the small intestine and adipose tissue, respectively, contribute to homeostasis of intestinal immune responses and metabolism. Accordingly, in this review, we summarize new functions of eosinophils demonstrated in recent studies and discuss their homeostatic functions. © 2017 The Korean Association of Immunologists.-
dc.description.sponsorshipInstitute for Basic Science-
dc.languageEnglish-
dc.publisherKorean Association of Immunologists-
dc.subjectAnti-inflammation-
dc.subjectEosinophils-
dc.subjectIgA-
dc.subjectIL-1R antagonist-
dc.subjectIL-4-
dc.subjectTh17 cells-
dc.titleRegulatory eosinophils in inflammation and metabolic disorders-
dc.typeReview-
dc.relation.issue1-
dc.relation.volume17-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage41-
dc.relation.lastpage47-
dc.relation.journaltitleImmune Network-
dc.identifier.doi10.4110/in.2017.17.1.41-
dc.identifier.wosidWOS:000408320600005-
dc.identifier.scopusid2-s2.0-85020061800-
dc.author.googleYang B.-G.-
dc.author.googleSeoh J.-Y.-
dc.author.googleJang M.H.-
dc.contributor.scopusid서주영(6603709174)-
dc.date.modifydate20181207113538-
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의과대학 > 의학과 > Journal papers
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