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dc.contributor.author김규보-
dc.contributor.author박경란-
dc.date.accessioned2018-12-07T16:30:20Z-
dc.date.available2018-12-07T16:30:20Z-
dc.date.issued2017-
dc.identifier.issn1598-2998-
dc.identifier.otherOAK-21499-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/247280-
dc.description.abstractPurpose This study was conducted to evaluate the impact of supraclavicular lymph node radiotherapy (SCNRT) on N1 breast cancer patients receiving post-lumpectomy whole-breast irradiation (WBI) and anthracycline plus taxane-based (AT) chemotherapy. Materials and Methods We performed a case-control analysis to compare the outcomes of WBI and WBI plus SCNRT (WBI+SCNRT). Among 1,147 patients with N1 breast cancer who received post-lumpectomy radiotherapy and AT-based chemotherapy in 12 hospitals, 542 were selected after propensity score matching. Patterns of failure, disease-free survival (DFS), distant metastasis-free survival (DMFS), and treatment-related toxicity were compared between groups. Results A total of 41 patients (7.6%) were found to have recurrence. Supraclavicular lymph node (SCN) failure was detected in three patients, two in WBI and one in WBI+SCNRT. All SCN failures were found simultaneously with distant metastasis. There was no significant difference in patterns of failure or survival between groups. The 5-year DFS and DMFS for patients with WBI and WBI+SCNRT were 94.4% versus 92.6% (p=0.50) and 95.1% versus 94.5% (p=0.99), respectively. The rates of lymphedema and radiation pneumonitis were significantly higher in the WBI+SCNRT than in the WBI. Conclusion We did not find a benefit of SCNRT for N1 breast cancer patients receiving AT-based chemotherapy. © 2017 by the Korean Cancer Association.-
dc.languageEnglish-
dc.publisherKorean Cancer Association-
dc.subjectAdjuvant radiotherapy-
dc.subjectBreast neoplasms-
dc.subjectCase-control studies-
dc.subjectLymphatic irradiation-
dc.subjectTaxane-
dc.titlePrognostic impact of elective supraclavicular nodal irradiation for patients with N1 breast cancer after lumpectomy and anthracycline plus taxane-based chemotherapy (KROG 1418): A multicenter case-controlled study-
dc.typeArticle-
dc.relation.issue4-
dc.relation.volume49-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage970-
dc.relation.lastpage980-
dc.relation.journaltitleCancer Research and Treatment-
dc.identifier.doi10.4143/crt.2016.382-
dc.identifier.wosidWOS:000413001500012-
dc.identifier.scopusid2-s2.0-85030762165-
dc.author.googleKim H.-
dc.author.googlePark W.-
dc.author.googleYu J.I.-
dc.author.googleChoi D.H.-
dc.author.googleHuh S.J.-
dc.author.googleKim Y.-J.-
dc.author.googleLee E.S.-
dc.author.googleLee K.S.-
dc.author.googleKang H.-S.-
dc.author.googlePark I.H.-
dc.author.googleShin K.H.-
dc.author.googleWee C.W.-
dc.author.googleKim K.-
dc.author.googlePark K.R.-
dc.author.googleKim Y.B.-
dc.author.googleAhn S.J.-
dc.author.googleLee J.H.-
dc.author.googleKim J.H.-
dc.author.googleChun M.-
dc.author.googleLee H.-S.-
dc.author.googleKim J.S.-
dc.author.googleCha J.-
dc.contributor.scopusid김규보(8213302900)-
dc.contributor.scopusid박경란(14040340300)-
dc.date.modifydate20181207113403-
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의과대학 > 의학과 > Journal papers
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