Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김규보 | * |
dc.contributor.author | 박경란 | * |
dc.date.accessioned | 2018-12-07T16:30:20Z | - |
dc.date.available | 2018-12-07T16:30:20Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 1598-2998 | * |
dc.identifier.other | OAK-21499 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/247280 | - |
dc.description.abstract | Purpose This study was conducted to evaluate the impact of supraclavicular lymph node radiotherapy (SCNRT) on N1 breast cancer patients receiving post-lumpectomy whole-breast irradiation (WBI) and anthracycline plus taxane-based (AT) chemotherapy. Materials and Methods We performed a case-control analysis to compare the outcomes of WBI and WBI plus SCNRT (WBI+SCNRT). Among 1,147 patients with N1 breast cancer who received post-lumpectomy radiotherapy and AT-based chemotherapy in 12 hospitals, 542 were selected after propensity score matching. Patterns of failure, disease-free survival (DFS), distant metastasis-free survival (DMFS), and treatment-related toxicity were compared between groups. Results A total of 41 patients (7.6%) were found to have recurrence. Supraclavicular lymph node (SCN) failure was detected in three patients, two in WBI and one in WBI+SCNRT. All SCN failures were found simultaneously with distant metastasis. There was no significant difference in patterns of failure or survival between groups. The 5-year DFS and DMFS for patients with WBI and WBI+SCNRT were 94.4% versus 92.6% (p=0.50) and 95.1% versus 94.5% (p=0.99), respectively. The rates of lymphedema and radiation pneumonitis were significantly higher in the WBI+SCNRT than in the WBI. Conclusion We did not find a benefit of SCNRT for N1 breast cancer patients receiving AT-based chemotherapy. © 2017 by the Korean Cancer Association. | * |
dc.language | English | * |
dc.publisher | Korean Cancer Association | * |
dc.subject | Adjuvant radiotherapy | * |
dc.subject | Breast neoplasms | * |
dc.subject | Case-control studies | * |
dc.subject | Lymphatic irradiation | * |
dc.subject | Taxane | * |
dc.title | Prognostic impact of elective supraclavicular nodal irradiation for patients with N1 breast cancer after lumpectomy and anthracycline plus taxane-based chemotherapy (KROG 1418): A multicenter case-controlled study | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 49 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 970 | * |
dc.relation.lastpage | 980 | * |
dc.relation.journaltitle | Cancer Research and Treatment | * |
dc.identifier.doi | 10.4143/crt.2016.382 | * |
dc.identifier.wosid | WOS:000413001500012 | * |
dc.identifier.scopusid | 2-s2.0-85030762165 | * |
dc.author.google | Kim H. | * |
dc.author.google | Park W. | * |
dc.author.google | Yu J.I. | * |
dc.author.google | Choi D.H. | * |
dc.author.google | Huh S.J. | * |
dc.author.google | Kim Y.-J. | * |
dc.author.google | Lee E.S. | * |
dc.author.google | Lee K.S. | * |
dc.author.google | Kang H.-S. | * |
dc.author.google | Park I.H. | * |
dc.author.google | Shin K.H. | * |
dc.author.google | Wee C.W. | * |
dc.author.google | Kim K. | * |
dc.author.google | Park K.R. | * |
dc.author.google | Kim Y.B. | * |
dc.author.google | Ahn S.J. | * |
dc.author.google | Lee J.H. | * |
dc.author.google | Kim J.H. | * |
dc.author.google | Chun M. | * |
dc.author.google | Lee H.-S. | * |
dc.author.google | Kim J.S. | * |
dc.author.google | Cha J. | * |
dc.contributor.scopusid | 김규보(8213302900) | * |
dc.contributor.scopusid | 박경란(14040340300;57203047823;57207108839;57308917900) | * |
dc.date.modifydate | 20240222162403 | * |