Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박시재 | * |
dc.date.accessioned | 2018-12-07T16:30:20Z | - |
dc.date.available | 2018-12-07T16:30:20Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0960-8524 | * |
dc.identifier.other | OAK-21501 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/247279 | - |
dc.description.abstract | This study examined nine expired industrial Corynebacterium glutamicum strains with high lysine producing capability for enhanced production of 5-AVA. C. glutamicum KCTC 1857 exhibiting the highest lysine production was transformed with either original Pseudomonas putida davBA genes, encoding the 5-AVA biosynthesis pathway, or C. glutamicum codon-optimized davBA genes. C. glutamicum KCTC 1857 expressing the original genes had superior cell viability and 5-AVA production capability compared to the other strain. This strain produced 39.93 g/L of 5-AVA, which is the highest titer reported to date in fed-batch fermentation from glucose. Indeed, Miscanthus hydrolysate solution prepared from a novel process, comprising pretreatment, hydrolysis, purification, and concentration, was used as feedstock for 5-AVA production. A total of 12.51 g/L 5-AVA was produced from the Miscanthus hydrolysate; this value is 34.7% higher than that obtained from glucose in batch fermentation. © 2017 Elsevier Ltd | * |
dc.language | English | * |
dc.publisher | Elsevier Ltd | * |
dc.subject | 5-Aminovaleric acid | * |
dc.subject | Corynebacterium glutamicum | * |
dc.subject | Metabolic engineering | * |
dc.subject | Miscanthus | * |
dc.subject | Pretreatment | * |
dc.title | Production of 5-aminovaleric acid in recombinant Corynebacterium glutamicum strains from a Miscanthus hydrolysate solution prepared by a newly developed Miscanthus hydrolysis process | * |
dc.type | Article | * |
dc.relation.volume | 245 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1692 | * |
dc.relation.lastpage | 1700 | * |
dc.relation.journaltitle | Bioresource Technology | * |
dc.identifier.doi | 10.1016/j.biortech.2017.05.131 | * |
dc.identifier.wosid | WOS:000413038300048 | * |
dc.identifier.scopusid | 2-s2.0-85020107107 | * |
dc.author.google | Joo J.C. | * |
dc.author.google | Oh Y.H. | * |
dc.author.google | Yu J.H. | * |
dc.author.google | Hyun S.M. | * |
dc.author.google | Khang T.U. | * |
dc.author.google | Kang K.H. | * |
dc.author.google | Song B.K. | * |
dc.author.google | Park K. | * |
dc.author.google | Oh M.-K. | * |
dc.author.google | Lee S.Y. | * |
dc.author.google | Park S.J. | * |
dc.contributor.scopusid | 박시재(57191670770) | * |
dc.date.modifydate | 20240322131024 | * |