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A prospective survey of atrial fibrillation management for real-world guideline adherence: Comparison study of drugs for symptom control and complication prevention of atrial fibrillation (CODE-AF) Registry
- Title
- A prospective survey of atrial fibrillation management for real-world guideline adherence: Comparison study of drugs for symptom control and complication prevention of atrial fibrillation (CODE-AF) Registry
- Authors
- Kim H.; Kim T.-H.; Cha M.-J.; Lee J.M.; Park J.; Park J.-K.; Kang K.-W.; Shim J.; Uhm J.-S.; Kim J.; Park H.W.; Choi E.-K.; Kim J.-B.; Kim C.; Lee Y.S.; Joung B.
- Ewha Authors
- 박준범
- SCOPUS Author ID
- 박준범
- Issue Date
- 2017
- Journal Title
- Korean Circulation Journal
- ISSN
- 1738-5520
- Citation
- Korean Circulation Journal vol. 47, no. 6, pp. 877 - 887
- Keywords
- Anticoagulant agent; Atrial fibrillation; Guidelines adherence; Registry
- Publisher
- Korean Society of Circulation
- Indexed
- SCIE; SCOPUS; KCI
- Document Type
- Review
- Abstract
- Background and Objectives: The aging population is rapidly increasing, and atrial fibrillation (AF) is becoming a significant public health burden in Asia, including Korea. This study evaluated current treatment patterns and guideline adherence of AF treatment. Methods: In a prospective observational registry (COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation [CODE-AF] registry), 6,275 patients with nonvalvular AF were consecutively enrolled between June 2016 and April 2017 from 10 tertiary hospitals in Korea. Results: The AF type was paroxysmal, persistent, and permanent in 65.3%, 30.0%, and 2.9% of patients, respectively. Underlying structural heart disease was present in 11.9%. Mean CHA2DS2-VASc was 2.7±1.7. Oral anticoagulation (OAC), rate control, and rhythm control were used in 70.1%, 53.9%, and 54.4% of patients, respectively. OAC was performed in 82.7% of patients with a high stroke risk. However, antithrombotic therapy was inadequately used in 53.4% of patients with a low stroke risk. For rate control in 192 patients with low ejection fraction (<40%), β-blocker (65.6%), digoxin (5.2%), or both (19.3%) were adequately used in 90.1% of patients; however, a calcium channel blocker was inadequately used in 9.9%. A rhythm control strategy was chosen in 54.4% of patients. The prescribing rate of class Ic antiarrythmics, dronedarone, and sotalol was 16.9% of patients with low ejection fraction. Conclusion: This study shows how successfully guidelines can be applied in the real world. The nonadherence rate was 17.2%, 9.9%, and 22.4% for stroke prevention, rate control, and rhythm control, respectively. © 2017. The Korean Society of Cardiology.
- DOI
- 10.4070/kcj.2017.0146
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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