View : 70 Download: 0

The effect of probiotics, antibiotics, and antipyretic analgesics on gut microbiota modification

Title
The effect of probiotics, antibiotics, and antipyretic analgesics on gut microbiota modification
Authors
Yun Y.Kim H.-N.Kim S.E.Chang Y.Ryu S.Shin H.Woo S.-Y.Kim H.-L.
Ewha Authors
김형래우소연김한나윤여준김송이
SCOPUS Author ID
김형래scopus; 우소연scopus; 김한나scopus; 윤여준scopusscopus
Issue Date
2017
Journal Title
Journal of Bacteriology and Virology
ISSN
1598-2467JCR Link
Citation
Journal of Bacteriology and Virology vol. 47, no. 1, pp. 64 - 74
Keywords
AntibioticsAntipyretic analgesicsGut microbiotaProbiotics
Publisher
The Korean Society for Mocrobiology / The Korean Society of Virology
Indexed
SCOPUS; KCI scopus
Document Type
Article
Abstract
Human gut microbial community is playing a critical role in human health and associated with different human disease. In parallel, probiotics, antibiotics, and antipyretic analgesics (AAs) were developed to improve human health or cure human diseases. We therefore examined how probiotics, antibiotics, and AAs influence to the gut microbiota. Three independent case/control studies were designed from the cross-sectional cohort data of 1,463 healthy Koreans. The composition of the gut microbiota in each case and control group was determined via 16S ribosomal RNA Illumina next-generation sequencing. The correlation between microbial taxa and the consumption of each drug was tested using zero-inflated Gaussian mixture models, with covariate adjustment of age, sex, and body mass index (BMI). Probiotics, antibiotics, and AAs consumption yielded the significant differences in the gut microbiota, represented the lower abundance of Megasphaera in probiotics, the higher abundance of Fusobacteria in antibiotics, and the higher abundance of Butyrivibrio and Verrucomicrobia in AAs, compared to each control group. The reduction of Erysipelotrichaceae family was common in three drugs consumption. © 2017, Chonnam National University Medical School. All rights reserved.
DOI
10.4167/jbv.2017.47.1.64
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE