Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이선영 | - |
dc.date.accessioned | 2018-11-21T16:30:56Z | - |
dc.date.available | 2018-11-21T16:30:56Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0013-726X | - |
dc.identifier.other | OAK-21889 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/246914 | - |
dc.description.abstract | Background and study aims: The present study aimed to determine the type of intravenous hydration that is best suited to reducing the incidence of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Patients and methods :In a prospective randomized multicenter trial, average-to-high risk patients who underwent first-time ERCP were randomly assigned to three groups (1:1:1) who received: aggressive intravenous hydration (3 mL/kg/h during ERCP, a 20-mL/kg bolus and 3 mL/kg/h for 8 hours after ERCP) with either lactated Ringer's solution (LRS) or normal saline solution (NSS), or standard intravenous hydration with LRS (1.5 mL/kg/h during and for 8 hours after ERCP). The primary end point was post-ERCP pancreatitis (PEP). Results :395 patients were enrolled, and 385 completed the protocols. The three groups showed no significant differences in demographic characteristics. There was a significant difference in the intention-to-treat (ITT) PEP rate between the aggressive LRS group (3.0 %, 95 % confidence interval [CI] 0.1 % - 5.9 %; 4 /132), the aggressive NSS group (6.7 %, 95 %CI 2.5 % - 10.9 %; 9 /134) and the standard LRS group (11.6 %, 95 %CI 6.1 % - 17.2 %; 15 /129; P = 0.03). In the two-group comparisons, the ITT PEP rate was significantly lower for the aggressive LRS group than for the standard LRS group (relative risk [RR] 0.26, 95 %CI 0.08 - 0.76; P = 0.008). There was no significant difference in the ITT PEP rate between the aggressive NSS group and the standard LRS group (RR 0.57, 95 %CI 0.26 - 1.27; P = 0.17). Conclusion :Aggressive hydration with LRS is the best approach to intravenous hydration for the prevention of PEP in average-to-high risk patients. © Georg Thieme Verlag KG Stuttgart. New York. | - |
dc.language | English | - |
dc.publisher | Georg Thieme Verlag | - |
dc.title | Aggressive intravenous hydration with lactated Ringer's solution for prevention of post-ERCP pancreatitis: A prospective randomized multicenter clinical trial | - |
dc.type | Article | - |
dc.relation.issue | 4 | - |
dc.relation.volume | 50 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 378 | - |
dc.relation.lastpage | 385 | - |
dc.relation.journaltitle | Endoscopy | - |
dc.identifier.doi | 10.1055/s-0043-122386 | - |
dc.identifier.wosid | WOS:000431270800014 | - |
dc.identifier.scopusid | 2-s2.0-85038351437 | - |
dc.author.google | Park C.-H. | - |
dc.author.google | Paik W.H. | - |
dc.author.google | Park E.T. | - |
dc.author.google | Shim C.S. | - |
dc.author.google | Lee T.Y. | - |
dc.author.google | Kang C. | - |
dc.author.google | Noh M.H. | - |
dc.author.google | Yi S.Y. | - |
dc.author.google | Lee J.K. | - |
dc.author.google | Hyun J.J. | - |
dc.contributor.scopusid | 이선영(7201404669;56218479400) | - |
dc.date.modifydate | 20221123111302 | - |