Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경효 | * |
dc.date.accessioned | 2018-11-21T16:30:34Z | - |
dc.date.available | 2018-11-21T16:30:34Z | - |
dc.date.issued | 2018 | * |
dc.identifier.issn | 2045-2322 | * |
dc.identifier.other | OAK-22266 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/246788 | - |
dc.description.abstract | Determination of the major serogroups is an important step for establishing a vaccine programme and management strategy targeting Neisseria meningitidis. From April 2010 to November 2016, a total of 25 N. meningitidis isolates were collected in South Korea, in collaboration with the Korean Society of Clinical Microbiology. Among isolates, 19 isolates were recovered from blood and/or cerebrospinal fluid (CSF) in 46 patients who suffered from invasive meningococcal disease (IMD), and six isolates were found in sputum or the throat. The most common serogroup was serogroup B (overall, 36%, n = 9/25; IMD, 37%, n = 7/19), which was isolated in every year of the research period except for 2011. There were five serogroup W isolates recovered from patients in military service. W was no longer isolated after initiation of a vaccine programme for military trainees, but serogroup B caused meningitis in an army recruit training centre in 2015. In MLST analysis, 14 sequence types were found, and all isolates belonging to W showed the same molecular epidemiologic characteristics (W:P1.5-1, 2-2:F3-9:ST-8912). All isolates showed susceptibility to ceftriaxone, meropenem, ciprofloxacin, minocycline, and rifampin; however, the susceptibility rates to penicillin and ampicillin for isolates with W and C capsules were 22% and 30%, respectively. © 2018 The Author(s). | * |
dc.language | English | * |
dc.publisher | Nature Publishing Group | * |
dc.title | Prevalence and serogroup changes of Neisseria meningitidis in South Korea | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 8 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Scientific Reports | * |
dc.identifier.doi | 10.1038/s41598-018-23365-8 | * |
dc.identifier.wosid | WOS:000428518500003 | * |
dc.identifier.scopusid | 2-s2.0-85044530820 | * |
dc.author.google | Lee H. | * |
dc.author.google | Seo Y. | * |
dc.author.google | Kim K.-H. | * |
dc.author.google | Lee K. | * |
dc.author.google | Choe K.-W. | * |
dc.contributor.scopusid | 김경효(35448653000) | * |
dc.date.modifydate | 20240301081003 | * |