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Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay
- Title
- Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay
- Authors
- Lim, Hyun Jeong; Lee, Eun-Hee; Lee, Sang-Don; Yoon, Yeomin; Son, Ahjeong
- Ewha Authors
- 이상돈; 손아정
- SCOPUS Author ID
- 이상돈; 손아정
- Issue Date
- 2018
- Journal Title
- CHEMOSPHERE
- ISSN
- 0045-6535
1879-1298
- Citation
- CHEMOSPHERE vol. 211, pp. 72 - 80
- Keywords
- Bisphenol A; Endocrine disrupting chemicals; Quantum dots; Aptamer; Aptasensor
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- The NanoAptamer assay is a bisphenol A (BPA) quantification method that uses magnetic beads, quantum dot nanoparticles, and a BPA-specific aptamer. In this study, screening of various consumer and household products for BPA was demonstrated utilizing the NanoAptamer assay. First, the experimental conditions suitable for BPA detection using the NanoAptamer assay were examined in terms of incubation time, temperature, and buffer composition. The range of BPA quantification via the NanoAptamer assay was determined to be 0.005-1000 ng/mL of BPA. The selectivity was confirmed by detecting BPA in an analog mixture containing bisphenol S and bisphenol F. Finally, a leaching experiment using 20 consumer and household products classified into 4 categories was performed to demonstrate the capability of the NanoAptamer assay for BPA detection. The experiment was validated by high-performance liquid chromatography analysis (correlation coefficient, r = 0.99). (C) 2018 Elsevier Ltd. All rights reserved.
- DOI
- 10.1016/j.chemosphere.2018.07.125
- Appears in Collections:
- 공과대학 > 환경공학과 > Journal papers
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