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Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay

Title
Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay
Authors
Lim H.J.Lee E.-H.Lee S.-D.Yoon Y.Son A.
Ewha Authors
이상돈손아정
SCOPUS Author ID
이상돈scopus; 손아정scopus
Issue Date
2018
Journal Title
Chemosphere
ISSN
0045-6535JCR Link
Citation
vol. 211, pp. 72 - 80
Keywords
AptamerAptasensorBisphenol AEndocrine disrupting chemicalsQuantum dots
Publisher
Elsevier Ltd
Indexed
SCI; SCIE; SCOPUS scopus
Abstract
The NanoAptamer assay is a bisphenol A (BPA) quantification method that uses magnetic beads, quantum dot nanoparticles, and a BPA-specific aptamer. In this study, screening of various consumer and household products for BPA was demonstrated utilizing the NanoAptamer assay. First, the experimental conditions suitable for BPA detection using the NanoAptamer assay were examined in terms of incubation time, temperature, and buffer composition. The range of BPA quantification via the NanoAptamer assay was determined to be 0.005–1000 ng/mL of BPA. The selectivity was confirmed by detecting BPA in an analog mixture containing bisphenol S and bisphenol F. Finally, a leaching experiment using 20 consumer and household products classified into 4 categories was performed to demonstrate the capability of the NanoAptamer assay for BPA detection. The experiment was validated by high-performance liquid chromatography analysis (correlation coefficient, r = 0.99). © 2018 Elsevier Ltd
DOI
10.1016/j.chemosphere.2018.07.125
Appears in Collections:
엘텍공과대학 > 환경공학전공 > Journal papers
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