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Self-immolative colorimetric, fluorescent and chemiluminescent chemosensors

Title
Self-immolative colorimetric, fluorescent and chemiluminescent chemosensors
Authors
Yan J.Lee S.Zhang A.Yoon J.
Ewha Authors
윤주영
SCOPUS Author ID
윤주영scopus
Issue Date
2018
Journal Title
Chemical Society Reviews
ISSN
0306-0012JCR Link
Citation
vol. 47, no. 18, pp. 6900 - 6916
Publisher
Royal Society of Chemistry
Indexed
SCI; SCIE; SCOPUS scopus
Abstract
Self-immolative chemistry features a cascade of disassembly reactions in response to external stimuli, which provides great opportunities to design new self-immolative chemosensors with advanced performance and/or functions. Self-immolative spacers in these chemosensors not only facilitate the linkage of designed triggers to various chromophores or fluorophores, but can also be used to solve inherent problems associated with native chemosensors, such as low reactivities, poor stabilities and slow response times. Their capacity for stimuli-responsive release through operation of a self-immolative reaction further enables integration of sophisticated functions into chemosensors, including signal amplification, enzyme activity localization, and drug monitoring. Significant advances have been made in the field of self-immolative chemosensors, leading to intriguing applications to sensitive detection of analytes, bioimaging and cancer theranostics. This tutorial review summarizes this recent progress with a focus on their design strategies and sensing mechanisms. © 2018 The Royal Society of Chemistry.
DOI
10.1039/c7cs00841d
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자연과학대학 > 화학·나노과학전공 > Journal papers
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