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N-alpha-acetyltransferase 10 (NAA10) in development: the role of NAA10

Title
N-alpha-acetyltransferase 10 (NAA10) in development: the role of NAA10
Authors
Lee, Mi-NiKweon, Hyae YonOh, Goo Taeg
Ewha Authors
오구택
SCOPUS Author ID
오구택scopus
Issue Date
2018
Journal Title
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613JCR Link

2092-6413JCR Link
Citation
EXPERIMENTAL AND MOLECULAR MEDICINE vol. 50
Publisher
NATURE PUBLISHING GROUP
Indexed
SCIE; SCOPUS; KCI WOS
Document Type
Review
Abstract
N-alpha-acetyltransferase 10 (NAA10) is a subunit of N-alpha-terminal protein acetyltransferase that plays a role in many biological processes. Among the six N-alpha-acetyltransferases (NATs) in eukaryotes, the biological significance of the N-terminal acetyl-activity of Naa10 has been the most studied. Recent findings in a few species, including humans, indicate that loss of N-terminal acetylation by NAA10 is associated with developmental defects. However, very little is known about the role of NAA10, and more research is required in relation to the developmental process. This review summarizes recent studies to understand the function of NAA10 in the development of multicellular organisms.
DOI
10.1038/s12276-018-0105-2
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자연과학대학 > 생명과학전공 > Journal papers
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