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The J-shape association of serum total IgE levels with age-related cataract

Title
The J-shape association of serum total IgE levels with age-related cataract
Authors
Park, SangshinChoi, Nam-Kyong
Ewha Authors
최남경
Issue Date
2018
Journal Title
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
ISSN
2222-3959JCR Link2227-4898JCR Link
Citation
vol. 11, no. 6, pp. 1009 - 1012
Keywords
IgEallergycataracteye
Publisher
IJO PRESS
Indexed
SCIE WOS
Abstract
AIM: To address the association between serum total IgE levels and age-related cataract in adults. METHODS: The study participants consisted of 1052 adults aged 40y or older in the Korean National Health and Nutrition Examination Survey 2010. We performed multivariable logistic regression analyses using the quartile cut-points of total IgE levels. RESULTS: The odds ratios (ORs) for nuclear and any cataract with >= 267 kU/L of serum IgE levels were 1.75 [95% confidence intervals (CI), 1.04-2.96] and 2.00 (95% CI, 1.223.27), respectively, comparing to 35-87 kU/L. Interestingly, participants with <= 35 kU/L of IgE levels (OR, 1.67; 95% CI, 1.02-2.72) also had higher risk for any cataract than those with 35-87 kU/L. The risk for any cataract (OR, 1.48; 95% CI, 1.03-2.13) was higher in participants with high total IgE levels (> 50 kU/L), comparing to normal participants. CONCLUSION: Our findings indicate a J-shaped relationship between serum IgE levels and age-related cataract.
DOI
10.18240/ijo.2018.06.19
Appears in Collections:
신산업융합대학 > 융합보건학과 > Journal papers
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