Minimally differentiated acute myelogenous leukemia presented with multiple cervical lymphadenopathy

Abstract

Lymphadenopathy is a relatively uncommon finding of minimally differentiated acute myelogenous leukemia(AML-M0). We experienced a case of AML-M0 in a 57-year-dd man initially presented with multiple cervical lymphadenopathy. Bone marrow aspiration revealed myeloblasts, which were negative for myeloperoxidase, Sudan black B, Periodic acid-Schiff, non-specific esterase and double esterase reaction. In cell surface marker studies, CD13, CD14, CD33, CD34, CD45 and HLA-DR were present. CT scan of neck demonstrated multiple lymphadenopathy at both internal jugular chains, spinal accessary chains and submandibular area. He died about two weeks after diagnosis without specific treatment.