Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안정자 | * |
dc.contributor.author | 우복희 | * |
dc.contributor.author | 김영주 | * |
dc.date.accessioned | 2018-06-02T08:14:11Z | - |
dc.date.available | 2018-06-02T08:14:11Z | - |
dc.date.issued | 1997 | * |
dc.identifier.issn | 0001-5563 | * |
dc.identifier.other | OAK-17694 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/244031 | - |
dc.description.abstract | OBJECTIVE: The purposes of this study was to determine the effect of bacterial endotoxin on the synthesis of interleukin-1β (IL-1β) and prostaglandin PG E., (PG E2) hy dispersed cells from human decidua, and to determine the inhibitory effect of anti-IL-1β and transforming growth factor-β, (TGF-β,) on the svnthcsis of ll.-lβ and PC; E., bv dispersed cells from human deridua. STUDY DESIGN: Human decidual cells in monolaver culture were treated with endotoxin. IL-lβ, endotoxin plus monoclonal antihuman ll.-lβ, endotoxin plus TGF-β,. The IL-lβ and PG EL, production were measured by E LISA and RIA. RESULTS: I) The PG EL, and IL-lβ synthesis stimulated with bacterial endotoxin bv decidual cells for 24 hours culture significantly increased in com pat isoii with controls. 2) The PG E.. and II.-l βsynthesis stimulated with bacterial endotoxin and anii-IL-lβ significantly decreased in comparison wiih controls. 3) The PG E, synthesis stimulated with bacterial endotoxin and TGF-β2, significantly decreased in comparison wilh controls. 4) The IL-lβ synthesis stimulated with bacterial endotoxin and TGF-β, significantly increased in comparison with controls. CONCLUSION: Bacterial endotoxin may induce the formation PG E2, through IL-lβ and endotoxin induced preterm labor mav be inhibited ami-IL-lβ and TGF-β2. | * |
dc.language | English | * |
dc.title | The effect of bacterial endotoxin on the synthesis of interleukin-lβ and prostaglandin e2 by dispersed cells from human decidua | * |
dc.type | Article | * |
dc.relation.issue | 1 PART II | * |
dc.relation.volume | 176 | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Acta Diabetologica Latina | * |
dc.identifier.scopusid | 2-s2.0-33748628237 | * |
dc.author.google | Kim Y.J. | * |
dc.author.google | Ahn J.J. | * |
dc.author.google | Woo B.H. | * |
dc.contributor.scopusid | 안정자(7403019711) | * |
dc.contributor.scopusid | 우복희(7004853990;36939080900) | * |
dc.contributor.scopusid | 김영주(55801681000) | * |
dc.date.modifydate | 20240423081003 | * |