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Nitric oxide synthesis in the adult and developing kidney

Title
Nitric oxide synthesis in the adult and developing kidney
Authors
Han K.-H.Jung J.-Y.Chung K.-Y.Kim H.Kim J.
Ewha Authors
정구용한기환
SCOPUS Author ID
정구용scopus; 한기환scopus
Issue Date
2006
Journal Title
Electrolyte and Blood Pressure
ISSN
1738-5997JCR Link
Citation
Electrolyte and Blood Pressure vol. 4, no. 1, pp. 1 - 7
Indexed
SCOPUS; KCI scopus
Document Type
Review
Abstract
Nitric oxide (NO) is synthesized within the adult and developing kidney and plays a critical role in the regulation of renal hemodynamics and tubule function. In the adult kidney, the regulation of NO synthesis is very cell type specific and subject to distinct control mechanisms of NO synthase (NOS) isoforms. Endothelial NOS (eNOS) is expressed in the endothelial cells of glomeruli, peritubular capillaries, and vascular bundles. Neuronal NOS (nNOS) is expressed in the tubular epithelial cells of the macula densa and inner medullary collecting duct. Furthermore, in the immature kidney, the expression of eNOS and nNOS shows unique patterns distinct from that is observed in the adult. This review will summarize the localization and presumable function of NOS isoforms in the adult and developing kidney.
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의과대학 > 의학과 > Journal papers
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