Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 장중현 | * |
dc.contributor.author | 이진화 | * |
dc.contributor.author | 천은미 | * |
dc.date.accessioned | 2018-06-02T08:14:00Z | - |
dc.date.available | 2018-06-02T08:14:00Z | - |
dc.date.issued | 2007 | * |
dc.identifier.issn | 1738-3536 | * |
dc.identifier.other | OAK-17813 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/243958 | - |
dc.description.abstract | Background: Triggering receptor expressed on myeloid cells 1 protein (TREM-1) is a cell surface molecule expressed on neutrophils and monocytes, and it plays an important role in myeloid cell-activated inflammatory response. The aim of this study was to investigate the diagnostic efficiency of soluble (s) TREM-1 in the patients who had pleural effusion from various causes. Methods: Forty-five patients with exudative pleural effusion were included in this study. The level of sTREM-1 was measured in both the serum and pleural fluids by immunoblot assay with using human-sTREM-1 antibody. Results: The pleural fluid sTREM-1 was significantly different in the three groups of exudative pleural effusion (p=0.011). Particularly, the patients with parapneumonic effusion were found to have significantly higher pleural fluid levels of sTREM-1 than patients with tuberculous (p<0.05) and malignant effusion, respectively (p<0.05). However, the serum sTREM-1 did not show a significant difference in the three groups. In order to evaluate the diagnostic utility of pleural fluid sTREM-1, the receiver operating characteristic (ROC) curve was constructed and the area under the curve (AUC) was 0.818 (p=0.001). Using a cutoff value of 103.5 pg/mL for the pleural fluid sTREM-1, the sensitivity and specificity were 73% and 81%, respectively, for differentiating parapneumonic effusion from tuberculous or malignant effusions. Conclusion: Pleural fluid sTREM-1 can be an additional marker for making the differential diagnosis of pleural effusion. | * |
dc.language | Korean | * |
dc.title | Diagnostic utility of pleural fluid soluble triggering receptor expressed on myeloid cells 1 protein in patients with exudative pleural effusion | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 62 | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 499 | * |
dc.relation.lastpage | 505 | * |
dc.relation.journaltitle | Tuberculosis and Respiratory Diseases | * |
dc.identifier.scopusid | 2-s2.0-34447329915 | * |
dc.author.google | Yun S.S. | * |
dc.author.google | Jin H.L. | * |
dc.author.google | Eun M.C. | * |
dc.author.google | Jung H.C. | * |
dc.contributor.scopusid | 장중현(57193227620) | * |
dc.contributor.scopusid | 이진화(56646645800;58376333800) | * |
dc.contributor.scopusid | 천은미(13410658400) | * |
dc.date.modifydate | 20240419140935 | * |