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dc.contributor.author배문선-
dc.date.accessioned2018-05-30T08:14:14Z-
dc.date.available2018-05-30T08:14:14Z-
dc.date.issued2006-
dc.identifier.issn0969-8043-
dc.identifier.otherOAK-3132-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/243563-
dc.description.abstract99mTc-labeled 1-thio-β-d-glucose (99mTc-1-TG) was synthesized under different ligand concentrations. 1-Thio-β-d-glucose (1-TG) showed different chemical properties and higher stability at acid pH as compared to neutral and basic pH. Under different ligand concentrations, 99mTc-1-TG was obtained with high labeling efficiency of >97%, but the HPLC chromatogram varied with the ligand concentration. The results of a tumor cell uptake assay also depended on the ligand concentration. With the lowest ligand concentration tested (0.5 mg/ml of 1-TG), we obtained the highest uptake. With different glucose and insulin concentrations, 99mTc-1-TG uptake was not significantly different from that of [18F]FDG. © 2005 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.title99mTc-labeled 1-thio-β-d-glucose as a new tumor-seeking agent: Synthesis and tumor cell uptake assay-
dc.typeArticle-
dc.relation.issue2-
dc.relation.volume64-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage207-
dc.relation.lastpage215-
dc.relation.journaltitleApplied Radiation and Isotopes-
dc.identifier.doi10.1016/j.apradiso.2005.07.022-
dc.identifier.wosidWOS:000234824500010-
dc.identifier.scopusid2-s2.0-28044434673-
dc.author.googleJun Oh S.-
dc.author.googleRyu J.-S.-
dc.author.googleYoon E.-J.-
dc.author.googleSun Bae M.-
dc.author.googleJoo Choi S.-
dc.author.googleBae Park K.-
dc.author.googleHyuk Moon D.-
dc.date.modifydate20180529145053-
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의과대학 > 의학과 > Journal papers
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