Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이미애 | * |
dc.date.accessioned | 2018-05-30T08:14:02Z | - |
dc.date.available | 2018-05-30T08:14:02Z | - |
dc.date.issued | 2006 | * |
dc.identifier.issn | 1076-6294 | * |
dc.identifier.other | OAK-3272 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/243486 | - |
dc.description.abstract | Cefoxitin-resistant Escherichia coli and Klebsiella pneumoniae are relatively prevalent in Korea, suggesting dissemination of plasmid-mediated AmpC β-lactamases. In this study, 238 isolates of cefositin-resistant E. coli and K, pneumoniae (not including subspecies ozaenae and rhinoscleromatis) were collected in 2003 from 16 Korean hospitals. The prevalence of plasmid-mediated AmpC β-lactamases was determined by PCR. The AmpC gene alleles detected in E. coli and K. pneumoniae were blaDHA-1, 10 (8.6%) and 93 (76.2%); blaCMY-1-like, 14 (12.1%) and 2 (1.6%); and blaCMY-2-like, 38 (32.7%) and 1 (0.8%) isolates, respectively. The genes identified were blaDHA-1, blaCMY10-like, and blaCMY-2-like, and a new variant, blaCMY-18. Plasmid-mediated AmpC gene allele-positive isolates were present both in large city and in small province hospitals, as well as in isolates from outpatients. The proportions of plasmid-mediated AmpC gene-positive isolates were similar in both expanded spectrum β-lactamase (ESBL)-producing and -nonproducing isolates. In conclusion, DHA-1, CMY-2-like, and CMY-10-like plasmid-mediated AmpC β-lactamase-producing K. pneumoniae and E. coli isolates are widely disseminated in both large city and small province hospitals. Absence of blaCMY-1 and detection of a novel variant of blaCMY-2, blaCMY-18, indicate continued evolution of the prototype genes. Similar proportions of plasmid-mediated AmpC gene-positive isolates in both ESBL-producing and -nonproducing isolates suggest unhindered future spread of these resistances. © Mary Ann Liebert, Inc. | * |
dc.language | English | * |
dc.title | Prevalence of plasmid-mediated AmpC β-lactamases in Escherichia coli and Klebsiella pneumoniae in Korea | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 12 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 44 | * |
dc.relation.lastpage | 49 | * |
dc.relation.journaltitle | Microbial Drug Resistance | * |
dc.identifier.doi | 10.1089/mdr.2006.12.44 | * |
dc.identifier.wosid | WOS:000236686300009 | * |
dc.identifier.scopusid | 2-s2.0-33646075082 | * |
dc.author.google | Lee K. | * |
dc.author.google | Lee M. | * |
dc.author.google | Shin J.H. | * |
dc.author.google | Lee M.H. | * |
dc.author.google | Kang S.H. | * |
dc.author.google | Park A.J. | * |
dc.author.google | Yong D. | * |
dc.author.google | Chong Y. | * |
dc.contributor.scopusid | 이미애(7409114044) | * |
dc.date.modifydate | 20240118124940 | * |