Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 천은미 | - |
dc.date.accessioned | 2018-05-30T08:13:56Z | - |
dc.date.available | 2018-05-30T08:13:56Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0026-0495 | - |
dc.identifier.other | OAK-3361 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/243444 | - |
dc.description.abstract | High-sensitivity C-reactive protein (hs-CRP) is associated with an increased risk of cardiovascular disease and the development of type 2 diabetes mellitus. We analyzed the effects of lifestyle modifications including exercise training on hs-CRP in 47 overweight and obese adults. Subjects were divided into a lifestyle modification group (n = 23) (exercise and diet instruction) and a control group (n = 24) who did not participate in any lifestyle modification. After 3 months, body weight (80.8 ± 11.5 to 73.5 ± 10.7 kg, P < .01), total cholesterol (217 ± 38.4 to 178.0 ± 25.6 mg/dL, P < .01), low-density lipoprotein cholesterol (151.3 ± 34.9 to 116.7 ± 27.8 mg/dL, P < .01), Vo2peak (30.3 ± 5.1 to 37.1 ± 6.9 mL/[kg · min], P < .01), and log hs-CRP (0.75 ± 0.4 to 0.56 ± 0.3 mg/dL, P = .01) were significantly improved in the lifestyle modification group, but there was no significant improvement in the control group. Changes in log hs-CRP were associated with changes in Vo2peak (r = -0.41, P = .004) and changes in weight loss (r = 0.42, P = .004). In stepwise multiple regression analysis, weight loss (P = .034) and improved Vo2peak (P = .039) were independent predictors of the changes in hs-CRP. When grouped into quartiles according to decreasing weight and increasing Vo2peak, levels of changes in log hs-CRP improved across quartiles of weight loss (P < .05) and improved Vo2peak (P < .01). Thus, lifestyle changes including regular exercise training in overweight and obese adults decreased hs-CRP, and this was associated with weight loss and improved Vo2peak. © 2006 Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.title | Effects of lifestyle modifications on C-reactive protein: contribution of weight loss and improved aerobic capacity | - |
dc.type | Article | - |
dc.relation.issue | 6 | - |
dc.relation.volume | 55 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 825 | - |
dc.relation.lastpage | 831 | - |
dc.relation.journaltitle | Metabolism: Clinical and Experimental | - |
dc.identifier.doi | 10.1016/j.metabol.2006.02.010 | - |
dc.identifier.wosid | WOS:000238014000019 | - |
dc.identifier.scopusid | 2-s2.0-33745779504 | - |
dc.author.google | Jae S.Y. | - |
dc.author.google | Fernhall B. | - |
dc.author.google | Heffernan K.S. | - |
dc.author.google | Jeong M. | - |
dc.author.google | Chun E.M. | - |
dc.author.google | Sung J. | - |
dc.author.google | Lee S.H. | - |
dc.author.google | Lim Y.J. | - |
dc.author.google | Park W.H. | - |
dc.contributor.scopusid | 천은미(13410658400) | - |
dc.date.modifydate | 20230210134735 | - |